Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 8/20 | 0.67 |
| ▸ | MAOB | P27338 | 7/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23480394 | 0.84 | STING1 (0.81) | STING1 | |
| SCHEMBL23480325 | 0.83 | STING1 (0.69) | STING1MAPTTP53RXFP1 | |
| SCHEMBL23480294 | 0.82 | STING1 (0.77) | STING1 | |
| SCHEMBL21436936 | 0.81 | STING1 (1.00) | STING1 | |
| SCHEMBL23480367 | 0.79 | STING1 (0.72) | STING1MAOBMAPT | |
| SCHEMBL23480326 | 0.78 | STING1 (0.79) | STING1MAOBMAPT | |
| SCHEMBL31496318 | 0.77 | STING1 (0.77) | STING1MAOB | |
| SCHEMBL21406183 | 0.77 | STING1 (0.77) | STING1MAOB | |
| SCHEMBL23480366 | 0.77 | STING1 (0.69) | STING1MAOBMAPT | |
| SCHEMBL23480295 | 0.76 | STING1 (0.79) | STING1MAOBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021113679-A1 | DIMERIC COMPOUNDS AS STING AGONISTS | MERSANA THERAPEUTICS, INC. (US) | 2021-06-10 | — | — | WO | disclosed |