Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.38 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10949554 | 0.83 | KMT2A (0.40) | L3MBTL1KDM4EMTNR1AMTNR1BKMT2A | |
| SCHEMBL2082374 | 0.81 | L3MBTL1 (0.57) | L3MBTL1KDM4EMTNR1AMTNR1BPTGS2 | |
| SCHEMBL3056564 | 0.79 | L3MBTL1 (0.59) | L3MBTL1KDM4EMTNR1AMTNR1BHPGD | |
| SCHEMBL7881270 | 0.79 | L3MBTL1 (0.59) | L3MBTL1KDM4EMTNR1AMTNR1BKMT2A | |
| SCHEMBL29964960 | 0.78 | NR1H2 (0.42) | KMT2A | |
| SCHEMBL17078987 | 0.78 | NR1H2 (0.42) | KMT2A | |
| SCHEMBL3924468 | 0.78 | L3MBTL1 (0.57) | L3MBTL1KDM4EMTNR1AMTNR1BKMT2A | |
| SCHEMBL29834934 | 0.78 | L3MBTL1 (0.57) | L3MBTL1KDM4EMTNR1AMTNR1BKMT2A | |
| SCHEMBL20618589 | 0.78 | L3MBTL1 (0.57) | L3MBTL1KDM4EMTNR1AMTNR1BKMT2A | |
| SCHEMBL4535733 | 0.78 | L3MBTL1 (0.57) | L3MBTL1KDM4EMTNR1AMTNR1BHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021111124-A1 | POLYHETEROCYCLIC COMPOUNDS AS METTL3 INHIBITORS | STORM THERAPEUTICS LIMITED (GB) | 2021-06-10 | — | — | WO | disclosed |