Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | RHOA | P61586 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | ACHE | P22303 | 3/20 | 0.38 |
| ▸ | HRAS | P01112 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.34 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.34 |
| ▸ | CDK9 | P50750 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23485990 | 0.84 | RAD52 (0.43) | HPGDPOLBRAD52ALDH1A1ACHE | |
| SCHEMBL24995591 | 0.81 | SMN1; SMN2 (0.48) | SMN1; SMN2HPGDPOLBRAD52RHOA | |
| SCHEMBL23458122 | 0.81 | HPGD (0.53) | SMN1; SMN2HPGDPOLBRAD52ALDH1A1 | |
| SCHEMBL23485953 | 0.80 | ACHE (0.42) | POLBRHOAALDH1A1ACHEHRAS | |
| SCHEMBL23485855 | 0.79 | HPGD (0.51) | SMN1; SMN2HPGDPOLBRAD52ALDH1A1 | |
| SCHEMBL23486000 | 0.77 | SMN1; SMN2 (0.57) | SMN1; SMN2HPGDPOLBRAD52ALDH1A1 | |
| SCHEMBL23486003 | 0.74 | SMN1; SMN2 (0.46) | SMN1; SMN2HPGDALDH1A1LMNA | |
| SCHEMBL23458107 | 0.73 | SMN1; SMN2 (0.53) | SMN1; SMN2HPGDPOLBRAD52ALDH1A1 | |
| SCHEMBL23485973 | 0.73 | SMN1; SMN2 (0.53) | SMN1; SMN2HPGDPOLBRAD52ALDH1A1 | |
| SCHEMBL23485979 | 0.71 | HPGD (0.51) | SMN1; SMN2HPGDPOLBRAD52ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021110280-A1 | AMINOACRIDINE AND AMINOPYRENE DYES AND THEIR USE AS FLUORESCENT TAGS, IN PARTICULAR FOR CARBOHYDRATE ANALYSIS | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e. V. (DE) | 2021-06-10 | — | — | WO | disclosed |