Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.76 |
| ▸ | NPC1 | O15118 | 3/20 | 0.65 |
| ▸ | RAB9A | P51151 | 3/20 | 0.65 |
| ▸ | FAAH | O00519 | 1/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23486699 | 0.87 | TSHR (1.00) | TSHRNPC1RAB9AFAAHTDP1 | |
| SCHEMBL7313251 | 0.86 | KDM4E (0.77) | NPC1RAB9AFAAHTDP1LMNA | |
| SCHEMBL7303372 | 0.85 | ALOX5 (0.68) | TSHRNPC1RAB9AFAAHTDP1 | |
| SCHEMBL23486322 | 0.84 | TSHR (0.71) | TSHRNPC1RAB9AFAAHTDP1 | |
| SCHEMBL12994636 | 0.84 | TSHR (0.71) | TSHRNPC1RAB9AFAAHTDP1 | |
| SCHEMBL23486701 | 0.84 | TSHR (0.71) | TSHRNPC1RAB9AFAAHTDP1 | |
| SCHEMBL27652942 | 0.84 | NPC1 (0.83) | TSHRNPC1RAB9AFAAHTDP1 | |
| SCHEMBL28363606 | 0.82 | TDP1 (0.78) | TSHRNPC1RAB9ATDP1LMNA | |
| SCHEMBL23486694 | 0.82 | TSHR (0.67) | TSHRNPC1RAB9AFAAHTDP1 | |
| SCHEMBL13595574 | 0.82 | KDM4E (0.58) | TSHRFAAHTDP1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021110076-A1 | OXAMIDE DERIVATIVES, PREPARATION METHOD THEREFOR AND USE THEREOF IN MEDICINE | 深圳信立泰药业股份有限公司 | 2021-06-10 | — | — | WO | disclosed |