Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 4/20 | 0.47 |
| ▸ | PLG | P00747 | 1/20 | 0.47 |
| ▸ | PLAU | P00749 | 1/20 | 0.47 |
| ▸ | F11 | P03951 | 9/20 | 0.47 |
| ▸ | KLK1 | P06870 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.43 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.42 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23486654 | 0.87 | USP30 (0.45) | KLKB1PLGPLAUF11CYP1A2 | |
| SCHEMBL29758102 | 0.86 | MEN1 (0.44) | F11SMN1; SMN2MEN1KMT2AIDO1 | |
| SCHEMBL23486843 | 0.83 | CYP2D6 (0.51) | KLKB1PLGPLAUF11CYP1A2 | |
| SCHEMBL23486879 | 0.82 | F11 (0.46) | PLAUF11KLK1SMN1; SMN2MEN1 | |
| SCHEMBL30680353 | 0.80 | KLKB1 (0.54) | KLKB1PLGPLAUF11CYP1A2 | |
| SCHEMBL23466764 | 0.80 | KLKB1 (0.54) | KLKB1PLGPLAUF11CYP1A2 | |
| SCHEMBL23466422 | 0.80 | F11 (0.47) | KLKB1F11CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL29758126 | 0.80 | F11 (0.47) | KLKB1F11CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL23466421 | 0.80 | F11 (0.47) | KLKB1F11CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL23486573 | 0.79 | F11 (0.46) | KLKB1PLGPLAUF11KLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114728917-B | Oxamide derivative, preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2023-12-08 | — | — | CN | disclosed |
| CN-114728917-A | Oxamide derivative, preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2022-07-08 | — | — | CN | disclosed |
| WO-2021110076-A1 | OXAMIDE DERIVATIVES, PREPARATION METHOD THEREFOR AND USE THEREOF IN MEDICINE | 深圳信立泰药业股份有限公司 | 2021-06-10 | — | — | WO | disclosed |