Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31320075 | 1.00 | SMN1; SMN2 (0.41) | SMN1; SMN2HSD17B10HPGDGAAALDH1A1 | |
| SCHEMBL23695127 | 0.93 | HSD17B10 (0.41) | SMN1; SMN2HSD17B10HPGDALDH1A1MEN1 | |
| SCHEMBL23695128 | 0.93 | HSD17B10 (0.41) | SMN1; SMN2HSD17B10HPGDALDH1A1MEN1 | |
| SCHEMBL7841633 | 0.90 | ATM (0.39) | SMN1; SMN2HSD17B10HPGDGAAALDH1A1 | |
| SCHEMBL24047701 | 0.87 | HSD17B10 (0.50) | SMN1; SMN2HSD17B10HPGDALDH1A1RECQL | |
| SCHEMBL1439128 | 0.87 | HSD17B10 (0.50) | SMN1; SMN2HSD17B10HPGDALDH1A1RECQL | |
| SCHEMBL26430589 | 0.87 | HSD17B10 (0.50) | SMN1; SMN2HSD17B10HPGDALDH1A1RECQL | |
| SCHEMBL31008158 | 0.87 | SMN1; SMN2 (0.38) | SMN1; SMN2HSD17B10HPGDGAAALDH1A1 | |
| SCHEMBL31320051 | 0.85 | SMN1; SMN2 (0.39) | SMN1; SMN2HSD17B10HPGDKMT2ARECQL | |
| SCHEMBL24962291 | 0.83 | SMN1; SMN2 (0.35) | SMN1; SMN2HSD17B10HPGDALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4688741-A1 | COMPOUNDS FOR TREATING FIBROTIC DISEASES | Meta-Immune, Inc. (KR) | 2026-02-11 | — | — | EP | disclosed |
| WO-2024249867-A1 | COMPOUNDS FOR TREATING FIBROTIC DISEASES | AM SCIENCES (KR) | 2024-12-05 | — | — | WO | disclosed |
| EP-4289839-A1 | NOVEL AURORA KINASE INHIBITOR AND USE THEREOF | Wigen Biomedicine Technology (Shanghai) Co., Ltd. (CN) | 2023-12-13 | — | — | EP | disclosed |
| WO-2023184327-A1 | KINASE INHIBITORS, PREPARATION METHODS AND USES THEREOF | InventisBio Co., Ltd. (CN) | 2023-10-05 | — | — | WO | disclosed |
| WO-2021110009-A1 | NOVEL AURORA KINASE INHIBITOR AND USE THEREOF | 微境生物医药科技(上海)有限公司 | 2021-06-10 | — | — | WO | disclosed |