Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23487150 | 0.87 | SMN1; SMN2 (0.41) | SMN1; SMN2OPRK1HSD17B10HPGDRECQL | |
| SCHEMBL31320075 | 0.87 | SMN1; SMN2 (0.41) | SMN1; SMN2OPRK1HSD17B10HPGDRECQL | |
| SCHEMBL7841633 | 0.82 | ATM (0.39) | SMN1; SMN2OPRK1HSD17B10HPGDRECQL | |
| SCHEMBL30566525 | 0.82 | HSD17B10 (0.39) | SMN1; SMN2HSD17B10HPGDALDH1A1CHRM2 | |
| SCHEMBL15594469 | 0.82 | HSD17B10 (0.39) | SMN1; SMN2HSD17B10HPGDALDH1A1CHRM2 | |
| SCHEMBL23695127 | 0.80 | HSD17B10 (0.41) | SMN1; SMN2HSD17B10HPGDRECQLPTPN2 | |
| SCHEMBL23695128 | 0.80 | HSD17B10 (0.41) | SMN1; SMN2HSD17B10HPGDRECQLPTPN2 | |
| SCHEMBL24962291 | 0.79 | SMN1; SMN2 (0.35) | SMN1; SMN2OPRK1HSD17B10HPGDALDH1A1 | |
| SCHEMBL21679124 | 0.79 | SMN1; SMN2 (0.43) | SMN1; SMN2HSD17B10HPGDRECQLPTPN2 | |
| SCHEMBL14157186 | 0.79 | SMN1; SMN2 (0.43) | SMN1; SMN2HSD17B10HPGDRECQLPTPN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118488957-A | Spirotricyclic RIPK1 inhibitors and methods of use thereof | 默沙东有限责任公司 | 2024-08-13 | — | — | CN | disclosed |