SCHEMBL23487154

SCHEMBL23487154

CC(Nc1nccs1)[C@H](C)F

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FDPS P14324 1/20 0.47
CSF1R P07333 1/20 0.41
LTK P29376 1/20 0.41
MAPK8 P45983 1/20 0.41
MAPK9 P45984 1/20 0.41
CDK7 P50613 1/20 0.41
CDK9 P50750 1/20 0.41
RPS6KA3 P51812 1/20 0.41
CDK5 Q00535 1/20 0.41
PTK2 Q05397 1/20 0.41
CAMK1D Q8IU85 1/20 0.41
CLK4 Q9HAZ1 1/20 0.41
ALK Q9UM73 1/20 0.41
DYRK1B Q9Y463 1/20 0.41
ALDH1A1 P00352 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
FFAR2 O15552 3/20 0.38
LMNA P02545 2/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
TSHR P16473 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL577833 0.84
SCHEMBL13574526 0.77 FDPS (0.47) FDPSALDH1A1TDP1FFAR2LMNA
SCHEMBL4695990 0.77 FDPS (0.47) FDPSALDH1A1TDP1FFAR2LMNA
SCHEMBL13996006 0.76 FDPS (0.46) FDPSCSF1RLTKMAPK8MAPK9
SCHEMBL972532 0.76 FDPS (0.46) FDPSCSF1RLTKMAPK8MAPK9
SCHEMBL1204712 0.74 CYP1A2 (0.46) FDPSALDH1A1FFAR2LMNASMN1; SMN2
SCHEMBL22826936 0.74 FDPS (0.45) FDPSCSF1RLTKMAPK8MAPK9
SCHEMBL30566396 0.73 FDPS (0.47) FDPSCSF1RLTKMAPK8MAPK9
SCHEMBL17198537 0.71
SCHEMBL13574496 0.71 FDPS (0.49) FDPSCDK5ALDH1A1TDP1FFAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021110009-A1 NOVEL AURORA KINASE INHIBITOR AND USE THEREOF 微境生物医药科技(上海)有限公司 2021-06-10 WO disclosed