SCHEMBL23487308

SCHEMBL23487308

Cc1ccc(-c2ccc3c(c2)c2ccccc2n3-c2cc(-c3nc(-c4ccccc4)cc(-c4ccccc4)n3)cc(-n3c4ccccc4c4cc(-c5ccc(C)cc5)ccc43)c2C#N)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA1 P30542 6/20 0.46
ADORA2A P29274 5/20 0.46
KDM4E B2RXH2 2/20 0.46
HPGD P15428 2/20 0.46
PPARG P37231 1/20 0.46
NCOA2 Q15596 1/20 0.46
NCOA1 Q15788 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
NCOA3 Q9Y6Q9 1/20 0.46
L3MBTL1 Q9Y468 2/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
ALDH1A1 P00352 2/20 0.40
MAPT P10636 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
PDE9A O76083 1/20 0.39
PDE1C Q14123 1/20 0.39
SQOR Q9Y6N5 4/20 0.39
AGTR1 P30556 1/20 0.38
ADORA2B P29275 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23487313 0.97 ADORA1 (0.48) ADORA1ADORA2AKDM4EHPGDPPARG
SCHEMBL22563547 0.95 SQOR (0.40) ADORA1ADORA2AKDM4EHPGDPPARG
SCHEMBL21108796 0.94 PDE9A (0.40) ADORA1ADORA2AKDM4EHPGDPPARG
SCHEMBL22563585 0.93 ADORA2A (0.47) ADORA1ADORA2AKDM4EHPGDPPARG
SCHEMBL23487670 0.93 HPGD (0.40) ADORA1ADORA2AKDM4EHPGDPPARG
SCHEMBL19913306 0.93 ADORA1 (0.46) ADORA1ADORA2AKDM4EHPGDPPARG
SCHEMBL22563685 0.93 KDM4E (0.43) ADORA1ADORA2AKDM4EHPGDPPARG
SCHEMBL21279044 0.91 SQOR (0.39) ADORA1ADORA2AKDM4EHPGDPPARG
SCHEMBL22563575 0.91 ADORA1 (0.41) ADORA1ADORA2AKDM4EHPGDPPARG
SCHEMBL22563384 0.91 ABCG2 (0.41) ADORA1ADORA2AKDM4EL3MBTL1SQOR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210175434-A1 ORGANIC MOLECULES FOR USE IN ORGANIC OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2021-06-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210175434-A1 ORGANIC MOLECULES FOR USE IN ORGANIC OPTOELECTRONIC DEVICES OR10J3, OR51E2, OCIAD2 ADORA1 4564/4885ADORA2A 4354/4885KDM4E 4619/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.