SCHEMBL23487356

SCHEMBL23487356

Cc1cccc(-c2ccc3c4ccccc4n(-c4cc(C#N)c(-c5nc(C)cc(C)n5)cc4-n4c5ccccc5c5ccc(-c6cccc(C)c6)cc54)c3c2)c1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AR P10275 1/20 0.37
F2 P00734 1/20 0.35
PLAU P00749 1/20 0.35
ELANE P08246 1/20 0.35
CTRB1 P17538 1/20 0.35
ADORA2A P29274 1/20 0.35
ADORA1 P30542 1/20 0.35
IMPDH2 P12268 1/20 0.35
LRRK2 Q5S007 2/20 0.34
KDM4A O75164 1/20 0.34
KDM5B Q9UGL1 1/20 0.34
KDM4E B2RXH2 2/20 0.34
S1PR4 O95977 1/20 0.34
ALDH1A1 P00352 1/20 0.34
GLA P06280 1/20 0.34
GAA P10253 1/20 0.34
HPGD P15428 1/20 0.34
S1PR1 P21453 1/20 0.34
ABCG2 Q9UNQ0 2/20 0.33
MAPT P10636 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23487653 0.96 AR (0.40) ARADORA2AADORA1IMPDH2LRRK2
SCHEMBL23487765 0.94 AR (0.37) ARF2PLAUELANECTRB1
SCHEMBL23487749 0.93 GRIN1 (0.33) KDM5BKDM4EALDH1A1GLAHPGD
SCHEMBL23487292 0.93 CYP1A2 (0.38) KDM4EALDH1A1GLAHPGDABCG2
SCHEMBL21108756 0.92 AR (0.37) ARF2PLAUELANECTRB1
SCHEMBL23487650 0.92 MAOA (0.33) ARADORA2AADORA1KDM4EALDH1A1
SCHEMBL23487237 0.91 ABCG2 (0.41) ADORA2AKDM4EALDH1A1ABCG2MAPT
SCHEMBL23487766 0.91 AR (0.39) ARF2PLAUELANECTRB1
SCHEMBL22563494 0.89 CYP1A2 (0.40) KDM4EALDH1A1GLAHPGDABCG2
SCHEMBL22563563 0.89 GRM2 (0.37) F2PLAUELANECTRB1IMPDH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210175434-A1 ORGANIC MOLECULES FOR USE IN ORGANIC OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2021-06-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210175434-A1 ORGANIC MOLECULES FOR USE IN ORGANIC OPTOELECTRONIC DEVICES OR10J3, OR51E2, OCIAD2 AR 4552/4885F2 594/4885PLAU 350/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.