SCHEMBL23487527

SCHEMBL23487527

CC(C)(C)OC(=O)N1CCN(S(=O)(=O)CI)CC1

nearest known ligand 0.47

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
TGM2 P21980 10/20 0.43
F13A1 P00488 7/20 0.43
TGM1 P22735 4/20 0.43
STS P08842 1/20 0.42
NR1H2 P55055 1/20 0.42
GPR119 Q8TDV5 1/20 0.41
HPGD P15428 1/20 0.41
EPHX2 P34913 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2249760 0.88 USP2 (0.51) USP2SMN1; SMN2TGM2F13A1TGM1
SCHEMBL5214356 0.85 USP2 (0.43) USP2SMN1; SMN2TGM2F13A1TGM1
SCHEMBL16415215 0.84 USP2 (0.47) USP2SMN1; SMN2TGM2F13A1TGM1
SCHEMBL56379 0.83 USP2 (0.53) USP2SMN1; SMN2TGM2F13A1TGM1
SCHEMBL2253618 0.83 SMN1; SMN2 (0.46) USP2SMN1; SMN2TGM2F13A1TGM1
SCHEMBL5717360 0.83 USP2 (0.46) USP2SMN1; SMN2TGM2F13A1TGM1
SCHEMBL2251415 0.81 USP2 (0.45) USP2SMN1; SMN2TGM2F13A1TGM1
SCHEMBL26113743 0.81 USP2 (0.45) USP2SMN1; SMN2TGM2F13A1TGM1
SCHEMBL25470758 0.81 L3MBTL1 (0.46) USP2SMN1; SMN2TGM2F13A1TGM1
Hydrochloric Acid SCHEMBL12501570 0.80 USP2 (0.44) USP2SMN1; SMN2TGM2F13A1TGM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021112626-A1 NOVEL INDIRUBIN DERIVATIVE AND USE THEREOF 주식회사 펠레메드 2021-06-10 WO disclosed