SCHEMBL23487586

SCHEMBL23487586

Cc1ccc(-c2ccc3c(c2)c2ccccc2n3-c2cc(C#N)cc(-n3c4ccccc4c4cc(-c5ccc(C)cc5)ccc43)c2-c2nc(C)cc(C)n2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGER4 P35408 4/20 0.39
ABCG2 Q9UNQ0 2/20 0.35
PDE9A O76083 2/20 0.35
PDE1C Q14123 2/20 0.35
MAPKAPK2 P49137 1/20 0.35
NPY5R Q15761 2/20 0.34
MAPT P10636 3/20 0.33
KDM4E B2RXH2 2/20 0.33
ALDH1A1 P00352 2/20 0.33
HPGD P15428 2/20 0.33
LMNA P02545 2/20 0.33
HTT P42858 2/20 0.33
GAA P10253 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
CASP1 P29466 1/20 0.33
HSD17B10 Q99714 1/20 0.33
PIK3CD O00329 1/20 0.32
PIK3CA P42336 1/20 0.32
HSD11B1 P28845 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22563366 0.94 MAPKAPK2 (0.38) PTGER4ABCG2MAPKAPK2ALDH1A1PIK3CD
SCHEMBL19913282 0.91 PTGER4 (0.39) PTGER4PDE9APDE1CMAPKAPK2NPY5R
SCHEMBL22563500 0.88 ABCG2 (0.41) PTGER4ABCG2ALDH1A1LMNAHSD17B10
SCHEMBL23487587 0.88 CHEK1 (0.38) ABCG2MAPKAPK2ALDH1A1PIK3CDPIK3CA
SCHEMBL22268473 0.88 PTGER4 (0.40) PTGER4ABCG2PDE9APDE1CMAPKAPK2
SCHEMBL22563427 0.87 PTGER4 (0.36) PTGER4ABCG2PDE9APDE1CMAPT
SCHEMBL21414129 0.87 PDE9A (0.39) PTGER4PDE9APDE1CMAPKAPK2MAPT
SCHEMBL23487620 0.86 ABCG2 (0.35) PTGER4ABCG2HSD11B1
SCHEMBL22563587 0.86 ABCG2 (0.36) PTGER4ABCG2
SCHEMBL22563556 0.86 ABCG2 (0.43) ABCG2ALDH1A1LMNAHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210175434-A1 ORGANIC MOLECULES FOR USE IN ORGANIC OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2021-06-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210175434-A1 ORGANIC MOLECULES FOR USE IN ORGANIC OPTOELECTRONIC DEVICES OR10J3, OR51E2, OCIAD2 PTGER4 1486/4885ABCG2 2612/4885PDE9A 4006/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.