SCHEMBL19913282

SCHEMBL19913282

Cc1ccc(-c2ccc3c(c2)c2ccccc2n3-c2cc(C#N)cc(-n3c4ccccc4c4cc(-c5ccc(C)cc5)ccc43)c2-c2cc(C)nc(C)c2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGER4 P35408 2/20 0.39
PDE9A O76083 2/20 0.36
PDE1C Q14123 2/20 0.36
KDM4E B2RXH2 2/20 0.34
ALDH1A1 P00352 2/20 0.34
MAPT P10636 2/20 0.34
HPGD P15428 2/20 0.34
MAPKAPK2 P49137 1/20 0.34
LMNA P02545 1/20 0.34
GAA P10253 1/20 0.34
HTT P42858 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
NPY5R Q15761 2/20 0.33
CASP1 P29466 1/20 0.32
HSD17B10 Q99714 1/20 0.32
PIK3CD O00329 1/20 0.31
PIK3CA P42336 1/20 0.31
IRAK4 Q9NWZ3 1/20 0.31
HSD11B1 P28845 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19909173 0.94 MAPKAPK2 (0.37) ALDH1A1MAPKAPK2PIK3CDPIK3CAIRAK4
SCHEMBL23487586 0.91 PTGER4 (0.39) PTGER4PDE9APDE1CKDM4EALDH1A1
SCHEMBL22170356 0.91 PTGER4 (0.36) PTGER4PDE9APDE1CKDM4EALDH1A1
SCHEMBL21414129 0.91 PDE9A (0.39) PTGER4PDE9APDE1CKDM4EALDH1A1
SCHEMBL19909387 0.89 MEN1 (0.35) PTGER4PDE9APDE1CKDM4EALDH1A1
SCHEMBL19909538 0.89 PDE9A (0.35) PTGER4PDE9APDE1CKDM4EALDH1A1
SCHEMBL19913153 0.88 MAPK14 (0.40) PTGER4PDE9APDE1CKDM4EALDH1A1
SCHEMBL21546727 0.88 MCHR1 (0.38) PTGER4PDE9APDE1CKDM4EALDH1A1
SCHEMBL19913283 0.87 CHEK1 (0.37) ALDH1A1MAPKAPK2PIK3CDPIK3CAIRAK4
SCHEMBL19913286 0.87 IRAK4 (0.34) PTGER4PDE9APDE1CKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10665792-B2 Organic molecules for use in optoelectronic devices CYNORA GMBH (DE) 2020-05-26 US disclosed
US-20180062085-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2018-03-01 US disclosed
US-20180062085-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2018-03-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10665792-B2 Organic molecules for use in optoelectronic devices OR10J3, CFD, AOX1 PTGER4 1386/4885PDE9A 4739/4885PDE1C 4778/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.