Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.68 |
| ▸ | NPC1 | O15118 | 1/20 | 0.68 |
| ▸ | RAB9A | P51151 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.52 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23488102 | 0.89 | KDM4E (0.80) | KDM4ESMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL17694678 | 0.86 | KDM4E (0.78) | KDM4ESMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL4726835 | 0.81 | NPC1 (0.75) | KDM4ESMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL1695688 | 0.80 | KDM4E (0.66) | KDM4ESMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL1695687 | 0.80 | KDM4E (0.66) | KDM4ESMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL11427962 | 0.80 | KDM4E (0.72) | KDM4ESMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL16212418 | 0.80 | KDM4E (0.66) | KDM4ESMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL6157404 | 0.77 | KDM4E (0.61) | KDM4ESMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL6157401 | 0.77 | KDM4E (0.61) | KDM4ESMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL3476282 | 0.76 | KDM4E (0.67) | KDM4ESMN1; SMN2NPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210170033-A1 | NOVEL CONJUGATES OF A PHARMACEUTICAL AGENT AND A MOIETY CAPABLE OF BINDING TO A GLUCOSE SENSING PROTEIN | SANOFI (FR) | 2021-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210170033-A1 | NOVEL CONJUGATES OF A PHARMACEUTICAL AGENT AND A MOIETY CAPABLE OF BINDING TO A GLUCOSE SENSING PROTEIN | GPR119, SLC2A8, SLC2A4 | KDM4E 4293/4885SMN1; SMN2 3945/4885NPC1 1840/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.