SCHEMBL23488795

SCHEMBL23488795

COC(=O)[C@H](CCCCNC(=O)CCCC(=O)NCc1cccc(COc2cc(OC)c(C(=O)N[C@H]3[C@@H](OC)O[C@H](CO)[C@@H](O)[C@@H]3O)cc2Cl)c1)NC(=O)OC(C)(C)C

nearest known ligand 0.37

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KLK7 P49862 2/20 0.37
KLK5 Q9Y337 2/20 0.37
POLB P06746 2/20 0.33
MEN1 O00255 1/20 0.33
MAPT P10636 1/20 0.33
KMT2A Q03164 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
CYP3A4 P08684 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA9 Q16790 1/20 0.32
CTSK P43235 1/20 0.31
BCHE P06276 1/20 0.31
ACHE P22303 1/20 0.31
ABCC8 Q09428 1/20 0.31
LGALS1 P09382 1/20 0.31
LGALS3 P17931 1/20 0.31
LGALS7; LGALS7B P47929 1/20 0.31
SIRT5 Q9NXA8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23488608 0.98 KLK7 (0.37) KLK7KLK5POLBMEN1MAPT
SCHEMBL23488696 0.98 KLK7 (0.37) KLK7KLK5POLBMEN1MAPT
SCHEMBL23488774 0.98 KLK7 (0.38) KLK7KLK5POLBMEN1MAPT
SCHEMBL23488617 0.93 KLK7 (0.37) KLK7KLK5MAPTNPSR1CA1
SCHEMBL23488246 0.92 KLK7 (0.36) KLK7KLK5MAPTNPSR1BCHE
SCHEMBL23488631 0.92 KLK7 (0.36) KLK7KLK5MAPTNPSR1BCHE
SCHEMBL23488776 0.92 KLK7 (0.36) KLK7KLK5MAPTNPSR1BCHE
SCHEMBL23488379 0.92 KLK7 (0.36) KLK7KLK5MAPTNPSR1BCHE
SCHEMBL23488530 0.91 KLK7 (0.38) KLK7KLK5POLBMEN1MAPT
SCHEMBL23488252 0.90 KLK7 (0.40) KLK7KLK5POLBMEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210170033-A1 NOVEL CONJUGATES OF A PHARMACEUTICAL AGENT AND A MOIETY CAPABLE OF BINDING TO A GLUCOSE SENSING PROTEIN SANOFI (FR) 2021-06-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210170033-A1 NOVEL CONJUGATES OF A PHARMACEUTICAL AGENT AND A MOIETY CAPABLE OF BINDING TO A GLUCOSE SENSING PROTEIN GPR119, SLC2A8, SLC2A4 KLK7 2859/4885KLK5 3345/4885POLB 4867/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.