Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | PPM1B | O75688 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14832401 | 1.00 | ALDH1A1 (0.54) | ALDH1A1MAPTMEN1KMT2APOLB | |
| SCHEMBL2336241 | 1.00 | ALDH1A1 (0.54) | ALDH1A1MAPTMEN1KMT2APOLB | |
| SCHEMBL2342273 | 1.00 | ALDH1A1 (0.54) | ALDH1A1MAPTMEN1KMT2APOLB | |
| SCHEMBL2336246 | 1.00 | ALDH1A1 (0.54) | ALDH1A1MAPTMEN1KMT2APOLB | |
| SCHEMBL2340142 | 0.98 | ALDH1A1 (0.57) | ALDH1A1MAPTMEN1KMT2APOLB | |
| SCHEMBL2340147 | 0.98 | ALDH1A1 (0.57) | ALDH1A1MAPTMEN1KMT2APOLB | |
| SCHEMBL2337316 | 0.98 | ALDH1A1 (0.57) | ALDH1A1MAPTMEN1KMT2APOLB | |
| SCHEMBL2340527 | 0.98 | ALDH1A1 (0.57) | ALDH1A1MAPTMEN1KMT2APOLB | |
| SCHEMBL2338896 | 0.96 | ALDH1A1 (0.50) | ALDH1A1MAPTMEN1KMT2APOLB | |
| SCHEMBL2338893 | 0.96 | ALDH1A1 (0.50) | ALDH1A1MAPTMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2358714-A1 | ALKYLCYCLOHEXYLETHERS OF DIHYDROTETRAAZABENZOAZULENES | F. Hoffmann-La Roche AG (CH) | 2011-08-24 | — | — | EP | disclosed |
| WO-2010057795-A1 | ALKYLCYCLOHEXYLETHERS OF DIHYDROTETRAAZABENZOAZULENES | F. HOFFMANN-LA ROCHE AG (CH) | 2010-05-27 | — | — | WO | disclosed |