Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TRPC5 | Q9UL62 | 4/20 | 0.43 |
| ▸ | TIPARP | Q7Z3E1 | 10/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23489927 | 0.93 | POLB (0.43) | POLBALDH1A1TRPC5TIPARP | |
| SCHEMBL31754098 | 0.92 | TRPC5 (0.47) | POLBALDH1A1TRPC5TIPARP | |
| SCHEMBL23489993 | 0.92 | TRPC5 (0.47) | POLBALDH1A1TRPC5TIPARP | |
| SCHEMBL23489990 | 0.92 | TRPC5 (0.47) | POLBALDH1A1TRPC5TIPARP | |
| SCHEMBL23490361 | 0.91 | POLB (0.44) | POLBALDH1A1TRPC5TIPARP | |
| SCHEMBL23573191 | 0.91 | POLB (0.44) | POLBALDH1A1TRPC5TIPARP | |
| SCHEMBL23573472 | 0.91 | POLB (0.44) | POLBALDH1A1TRPC5TIPARP | |
| SCHEMBL23490128 | 0.91 | POLB (0.44) | POLBALDH1A1TRPC5TIPARP | |
| SCHEMBL23490131 | 0.91 | POLB (0.44) | POLBALDH1A1TRPC5TIPARP | |
| SCHEMBL23573308 | 0.91 | POLB (0.48) | POLBALDH1A1TRPC5TIPARP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021113625-A1 | COMPOUNDS AND METHODS FOR CD73 MODULATION AND INDICATIONS THEREFOR | PLEXXIKON INC. (US) | 2021-06-10 | — | — | WO | disclosed |