Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | TRPC5 | Q9UL62 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 4/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TIPARP | Q7Z3E1 | 2/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23573525 | 0.92 | POLB (0.38) | ALDH1A1KDM4EHSD17B10KMT2APOLB | |
| SCHEMBL23573530 | 0.92 | POLB (0.38) | ALDH1A1KDM4EHSD17B10KMT2APOLB | |
| SCHEMBL23490005 | 0.91 | TIPARP (0.40) | ALDH1A1KDM4EHSD17B10KMT2APOLB | |
| SCHEMBL23489898 | 0.91 | ALDH1A1 (0.47) | ALDH1A1KDM4EHSD17B10KMT2APOLB | |
| SCHEMBL23490003 | 0.90 | ALDH1A1 (0.39) | ALDH1A1KDM4EHSD17B10KMT2APOLB | |
| SCHEMBL23490093 | 0.90 | ALDH1A1 (0.39) | ALDH1A1KDM4EHSD17B10KMT2APOLB | |
| SCHEMBL23490112 | 0.89 | POLB (0.40) | ALDH1A1KDM4EHSD17B10KMT2APOLB | |
| SCHEMBL23489888 | 0.87 | POLB (0.41) | ALDH1A1KDM4EHSD17B10KMT2APOLB | |
| SCHEMBL23608235 | 0.87 | POLB (0.41) | ALDH1A1KDM4EHSD17B10KMT2APOLB | |
| SCHEMBL23489900 | 0.87 | POLB (0.41) | ALDH1A1KDM4EHSD17B10KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210198239-A1 | COMPOUNDS AND METHODS FOR CD73 MODULATION AND INDICATIONS THEREFOR | PLEXXIKON INC. | 2021-07-01 | — | — | US | disclosed |
| WO-2021113625-A1 | COMPOUNDS AND METHODS FOR CD73 MODULATION AND INDICATIONS THEREFOR | PLEXXIKON INC. (US) | 2021-06-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210198239-A1 | COMPOUNDS AND METHODS FOR CD73 MODULATION AND INDICATIONS THEREFOR | ENTPD5, ADORA2A, ENTPD1 | ALDH1A1 216/4885KDM4E 2880/4885HSD17B10 2865/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.