Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.61 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL539233 | 1.00 | TSHR (0.61) | TSHRTHRBALDH1A1TDP1POLB | |
| SCHEMBL28973779 | 0.86 | TSHR (0.46) | TSHRTHRBALDH1A1TDP1 | |
| SCHEMBL8965555 | 0.85 | TSHR (0.53) | TSHRTHRBALDH1A1 | |
| SCHEMBL8965528 | 0.83 | TSHR (0.56) | TSHRTHRBALDH1A1 | |
| SCHEMBL26729541 | 0.83 | TSHR (0.61) | TSHRTHRBALDH1A1TDP1POLB | |
| SCHEMBL16209800 | 0.82 | THRB (0.56) | TSHRTHRBALDH1A1TDP1POLB | |
| SCHEMBL35507 | 0.81 | TSHR (0.63) | TSHRTHRBALDH1A1TDP1POLB | |
| SCHEMBL2845656 | 0.81 | TSHR (0.63) | TSHRTHRBALDH1A1TDP1POLB | |
| SCHEMBL11596898 | 0.81 | TSHR (0.63) | TSHRTHRBALDH1A1TDP1POLB | |
| SCHEMBL6433620 | 0.81 | TSHR (0.63) | TSHRTHRBALDH1A1TDP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0102312-A1 | Unsaturated polyurethanes | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1984-03-07 | — | — | EP | disclosed |