Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TRPC5 | Q9UL62 | 2/20 | 0.39 |
| ▸ | TIPARP | Q7Z3E1 | 7/20 | 0.36 |
| ▸ | CKS1B | P61024 | 1/20 | 0.36 |
| ▸ | SKP1 | P63208 | 1/20 | 0.36 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | KDM5A | P29375 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23489798 | 1.00 | POLB (0.42) | POLBALDH1A1TRPC5TIPARPCKS1B | |
| SCHEMBL23608250 | 1.00 | POLB (0.42) | POLBALDH1A1TRPC5TIPARPCKS1B | |
| SCHEMBL23490328 | 0.92 | POLB (0.48) | POLBALDH1A1TRPC5TIPARP | |
| SCHEMBL23573308 | 0.92 | POLB (0.48) | POLBALDH1A1TRPC5TIPARP | |
| SCHEMBL23490459 | 0.91 | POLB (0.44) | POLBALDH1A1TRPC5TIPARPDRD2 | |
| SCHEMBL23490433 | 0.91 | POLB (0.44) | POLBALDH1A1TRPC5TIPARPDRD2 | |
| SCHEMBL23490486 | 0.91 | DRD2 (0.44) | POLBALDH1A1TRPC5TIPARPCKS1B | |
| SCHEMBL23608203 | 0.91 | POLB (0.44) | POLBALDH1A1TRPC5TIPARPDRD2 | |
| SCHEMBL23489797 | 0.91 | POLB (0.45) | POLBALDH1A1TRPC5TIPARPKDM5A | |
| SCHEMBL23608268 | 0.91 | POLB (0.45) | POLBALDH1A1TRPC5TIPARPKDM5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021113625-A1 | COMPOUNDS AND METHODS FOR CD73 MODULATION AND INDICATIONS THEREFOR | PLEXXIKON INC. (US) | 2021-06-10 | — | — | WO | disclosed |