SCHEMBL234916

SCHEMBL234916

C1=C[N]SC=C1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL121041 0.67
SCHEMBL4449 0.58
SCHEMBL876230 0.55
SCHEMBL16534475 0.55
SCHEMBL30776105 0.55
SCHEMBL2384 0.47
Pyridazine SCHEMBL449549 0.47
SCHEMBL1042486 0.47
SCHEMBL708361 0.45
Water SCHEMBL8875322 0.45

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 509 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113816889-B 4-sulfimide-1H-pyrrole Mcl-1 inhibitor and anti-tumor medical application thereof 中国药科大学 2023-08-22 CN claimed
CN-113816889-A 4-sulfimide-1H-pyrrole Mcl-1 inhibitor and anti-tumor medical application thereof 中国药科大学 2021-12-21 CN claimed
CN-101687815-A Regioselective copper catalyzed synthesis of benzimidazoles and azabenzimidazoles SANOFI AVENTIS 2010-03-31 CN claimed
CN-101687865-A A regioselective metal catalyzed synthesis of annelated benzimidazoles and azabenzimidazoles SANOFI AVENTIS 2010-03-31 CN claimed
CN-101687809-A Transition metal catalyzed synthesis of 2H-indazoles SANOFI AVENTIS 2010-03-31 CN claimed
CN-101687734-A The coupled reaction method of catalytic terminal alkynes class of palladium and aryl tosylate class SANOFI AVENTIS 2010-03-31 CN claimed
CN-101687797-A Malonamide derivatives with antithrombotic activity SANOFI AVENTIS 2010-03-31 CN claimed
CN-101679358-A Pyrrole derivatives as p2y12 antagonists SANOFI AVENTIS 2010-03-24 CN claimed
CN-101663293-A Quinoline-carboxamide derivatives as p2y12 antagonists SANOFI AVENTIS 2010-03-03 CN claimed
CN-101657422-A Synthesizing of transition metal-catalyzed N-amino indole SANOFI AVENTIS FR 2010-02-24 CN claimed
WO-2003037895-A1 4-(6-MEMBERED)-HETEROARYL ACYL PYRROLIDINE DERIVATIVES AS HCV INHIBITORS GLAXO GROUP LIMITED (GB) 2003-05-08 WO claimed
JP-2001511781-A 2001-08-14 JP claimed
CN-1251523-A Sulfonamide derivatives LILLY CO ELI (US) 2000-04-26 CN claimed
WO-2000006539-A1 ALKENYL SULPHONAMIDE DERIVATIVES ELI LILLY AND COMPANY (US) 2000-02-10 WO claimed
WO-2000006157-A1 SULPHONAMIDE DERIVATIVES ELI LILLY AND COMPANY (US) 2000-02-10 WO claimed
WO-1998033496-A1 SULPHONAMIDE DERIVATIVES ELI LILLY AND COMPANY (US) 1998-08-06 WO claimed
US-5300497-A Broad spectrum antibiotics and bactericides; stable to beta-lactamase; effective against antibiotic-resistant bacteria TOYAMA CHEMICAL CO., LTD. (JP) 1994-04-05 US claimed
US-5185330-A Penicillins/ad/ TOYAMA CHEMICAL CO., LTD. (JP) 1993-02-09 US claimed
US-4420479-A 1-SUBSTITUTED, 2-AMINO-BENZIMIDAZOLES ELI LILLY AND COMPANY (US) 1983-12-13 US claimed
EP-0091795-A1 Olefinic benzimidazoles ELI LILLY AND COMPANY (US) 1983-10-19 EP claimed