Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | DAO | P14920 | 1/20 | 0.45 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 5/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 7/20 | 0.41 |
| ▸ | NR3C2 | P08235 | 7/20 | 0.41 |
| ▸ | PGR | P06401 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SNCA | P37840 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.38 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30765591 | 0.83 | NAMPT (0.48) | DAONAMPTCYP2C9MAPTF2 | |
| SCHEMBL18643043 | 0.81 | DAO (0.49) | DAOPDE3BPDE3ANAMPTCYP2C9 | |
| SCHEMBL23452339 | 0.78 | F2 (0.48) | DAONAMPTCYP2C9NR3C1NR3C2 | |
| SCHEMBL6066464 | 0.77 | LOXL2 (0.56) | CYP2A6DAOPDE3BPDE3ANR3C1 | |
| SCHEMBL1161438 | 0.77 | DAO (0.53) | DAOPDE3BPDE3ANAMPTCYP2C9 | |
| SCHEMBL1161735 | 0.77 | DAO (0.49) | DAOPDE3BPDE3ANAMPTCYP2C9 | |
| SCHEMBL8263862 | 0.77 | DAO (0.45) | DAOPDE3BPDE3ANAMPTCYP2C9 | |
| Hydrochloric Acid SCHEMBL27144900 | 0.76 | LOXL2 (0.55) | CYP2A6DAOPDE3BPDE3ANR3C1 | |
| Hydrochloric Acid SCHEMBL27140516 | 0.76 | LOXL2 (0.55) | CYP2A6DAOPDE3BPDE3ANR3C1 | |
| SCHEMBL26703893 | 0.75 | F2 (0.50) | DAOPDE3BPDE3ANAMPTNR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021113682-A1 | MASP-2 INHIBITORS AND METHODS OF USE | OMEROS CORPORATION (US) | 2021-06-10 | — | — | WO | disclosed |