SCHEMBL23494155

SCHEMBL23494155

C=CC(=O)OC(C)(C)CCC(C)C

nearest known ligand 0.46

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.46
CYP3A4 P08684 4/20 0.40
MEN1 O00255 1/20 0.40
ALOX15 P16050 1/20 0.40
KMT2A Q03164 1/20 0.40
ALDH1A1 P00352 5/20 0.36
TP53 P04637 3/20 0.36
HIF1A Q16665 3/20 0.36
MAPK1 P28482 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
TDP1 Q9NUW8 2/20 0.33
HPGD P15428 1/20 0.32
HSD17B10 Q99714 1/20 0.31
LMNA P02545 1/20 0.31
THRB P10828 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28034396 0.86 CYP3A4 (0.42) TSHRCYP3A4MEN1ALOX15KMT2A
SCHEMBL4590512 0.84 TSHR (0.40) TSHRCYP3A4ALDH1A1TP53HIF1A
SCHEMBL10292529 0.81 TSHR (0.48) TSHRCYP3A4MEN1ALOX15KMT2A
SCHEMBL22783272 0.81 TSHR (0.38) TSHRCYP3A4MEN1ALOX15KMT2A
SCHEMBL610708 0.80 RIPK1 (0.34) CYP3A4MEN1ALOX15KMT2AMAPK1
SCHEMBL15132277 0.80 TSHR (0.33) TSHRCYP3A4ALDH1A1TP53HIF1A
SCHEMBL18571473 0.79 TSHR (0.39) TSHRCYP3A4ALDH1A1TP53HIF1A
SCHEMBL868946 0.79 TSHR (0.43) TSHRCYP3A4ALDH1A1TP53HIF1A
SCHEMBL1108010 0.79 TSHR (0.44) TSHRCYP3A4ALDH1A1TP53HIF1A
SCHEMBL610707 0.78 CA1 (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112980543-B High viscosity index comb polymer viscosity modifiers and methods of using the same to alter lubricant viscosity 英菲诺姆国际有限公司 2023-12-19 CN disclosed
CN-112980549-B High viscosity index comb polymer viscosity modifiers and methods of using the same to alter lubricant viscosity 英菲诺姆国际有限公司 2023-12-15 CN disclosed
EP-3839018-B1 HIGH VISCOSITY INDEX COMB POLYMER VISCOSITY MODIFIERS AND METHODS OF MODIFYING LUBRICANT VISCOSITY USING SAME INFINEUM INT LTD (GB) 2023-10-18 EP disclosed
EP-3839019-B1 HIGH VISCOSITY INDEX COMB POLYMER VISCOSITY MODIFIERS AND METHODS OF MODIFYING LUBRICANT VISCOSITY USING SAME INFINEUM INT LTD (GB) 2023-08-02 EP disclosed
US-11685874-B2 High viscosity index comb polymer viscosity modifiers and methods of modifying lubricant viscosity using same INFINEUM INTERNATIONAL LIMITED (GB) 2023-06-27 US disclosed
US-11384311-B2 High viscosity index comb polymer viscosity modifiers and methods of modifying lubricant viscosity using same INFINEUM INTERNATIONAL LIMITED (GB) 2022-07-12 US disclosed
US-11365273-B2 High viscosity index comb polymer viscosity modifiers and methods of modifying lubricant viscosity using same INFINEUM INTERNATIONAL LIMITED (GB) 2022-06-21 US disclosed
US-20220169947-A1 High Viscosity Index Comb Polymer Viscosity Modifiers and Methods of Modifying Lubricant Viscosity Using Same INFINEUM INTERNATIONAL LIMITED (GB) 2022-06-02 US disclosed
US-20210189281-A1 High Viscosity Index Comb Polymer Viscosity Modifiers and Methods of Modifying Lubricant Viscosity Using Same lnfineum International Limited (GB) 2021-06-24 US disclosed
EP-3839017-A1 HIGH VISCOSITY INDEX COMB POLYMER VISCOSITY MODIFIERS AND METHODS OF MODIFYING LUBRICANT VISCOSITY USING SAME Infineum International Limited (GB) 2021-06-23 EP disclosed
EP-3839019-A1 HIGH VISCOSITY INDEX COMB POLYMER VISCOSITY MODIFIERS AND METHODS OF MODIFYING LUBRICANT VISCOSITY USING SAME Infineum International Limited (GB) 2021-06-23 EP disclosed
EP-3839018-A1 HIGH VISCOSITY INDEX COMB POLYMER VISCOSITY MODIFIERS AND METHODS OF MODIFYING LUBRICANT VISCOSITY USING SAME Infineum International Limited (GB) 2021-06-23 EP disclosed
CN-112980542-A High viscosity index comb polymer viscosity modifiers and methods of using the same to modify lubricant viscosity 英菲诺姆国际有限公司 2021-06-18 CN disclosed
CN-112980549-A High viscosity index comb polymer viscosity modifiers and methods of using the same to modify lubricant viscosity 英菲诺姆国际有限公司 2021-06-18 CN disclosed
CN-112980543-A High viscosity index comb polymer viscosity modifiers and methods of using the same to modify lubricant viscosity 英菲诺姆国际有限公司 2021-06-18 CN disclosed
US-20210179960-A1 High Viscosity Index Comb Copolymer Viscosity Modifiers and Methods of Modify Lubricant Viscosity Using Same INFINEUM INTERNATIONAL LIMITED (GB) 2021-06-17 US disclosed
US-20210179961-A1 High Viscosity Index Comb Copolymer Viscosity Modifiers and Methods of Modifying Lubricant Viscosity Using Same INFINEUM INTERNATIONAL LIMITED (GB) 2021-06-17 US disclosed
US-20210179760-A1 High Viscosity Index Comb Polymer Viscosity Modifiers and Methods of Modifying Lubricant Viscosity Using Same INFINEUM INTERNATIONAL LIMITED (GB) 2021-06-17 US disclosed
US-20210179965-A1 High Viscosity Index Comb Copolymer Viscosity Modifiers and Methods of Modifying Lubricant Viscosity Using Same INFINEUM INTERNATIONAL LIMITED (GB) 2021-06-17 US disclosed