SCHEMBL23494192

SCHEMBL23494192

C=CC(=O)OC(C)C(C)CCCC

nearest known ligand 0.50

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.50
HPGD P15428 1/20 0.47
THRB P10828 3/20 0.37
CTSK P43235 4/20 0.36
ALDH1A1 P00352 2/20 0.34
CYP3A4 P08684 1/20 0.34
LMNA P02545 2/20 0.34
CA2 P00918 2/20 0.34
CA1 P00915 1/20 0.34
THRA P10827 1/20 0.34
ATM Q13315 1/20 0.33
ZDHHC20 Q5W0Z9 1/20 0.33
ZDHHC2 Q9UIJ5 1/20 0.33
MAPK1 P28482 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5029204 0.93 TSHR (0.44) TSHRHPGDTHRBLMNATHRA
SCHEMBL23494097 0.89 TSHR (0.42) TSHRHPGDTHRBALDH1A1CYP3A4
SCHEMBL5027328 0.86 TSHR (0.50) TSHRHPGDTHRBCTSKALDH1A1
SCHEMBL9813234 0.86 TSHR (0.40) TSHRHPGDALDH1A1CYP3A4MAPK1
SCHEMBL9813114 0.84 TSHR (0.39) TSHRHPGDALDH1A1CYP3A4MAPK1
SCHEMBL9007754 0.84 TSHR (0.49) TSHRHPGDTHRBCTSKALDH1A1
SCHEMBL10398482 0.84 TSHR (0.49) TSHRHPGDTHRBCTSKALDH1A1
SCHEMBL7620025 0.83 TSHR (0.51) TSHRHPGDTHRBCTSKCYP3A4
SCHEMBL185499 0.81 TSHR (0.53) TSHRHPGDTHRBCTSKALDH1A1
SCHEMBL15820924 0.81 TSHR (0.46) TSHRHPGDTHRBCTSKALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112980543-B High viscosity index comb polymer viscosity modifiers and methods of using the same to alter lubricant viscosity 英菲诺姆国际有限公司 2023-12-19 CN disclosed
CN-112980549-B High viscosity index comb polymer viscosity modifiers and methods of using the same to alter lubricant viscosity 英菲诺姆国际有限公司 2023-12-15 CN disclosed
EP-3839018-B1 HIGH VISCOSITY INDEX COMB POLYMER VISCOSITY MODIFIERS AND METHODS OF MODIFYING LUBRICANT VISCOSITY USING SAME INFINEUM INT LTD (GB) 2023-10-18 EP disclosed
EP-3839019-B1 HIGH VISCOSITY INDEX COMB POLYMER VISCOSITY MODIFIERS AND METHODS OF MODIFYING LUBRICANT VISCOSITY USING SAME INFINEUM INT LTD (GB) 2023-08-02 EP disclosed
US-11685874-B2 High viscosity index comb polymer viscosity modifiers and methods of modifying lubricant viscosity using same INFINEUM INTERNATIONAL LIMITED (GB) 2023-06-27 US disclosed
US-11384311-B2 High viscosity index comb polymer viscosity modifiers and methods of modifying lubricant viscosity using same INFINEUM INTERNATIONAL LIMITED (GB) 2022-07-12 US disclosed
US-11365273-B2 High viscosity index comb polymer viscosity modifiers and methods of modifying lubricant viscosity using same INFINEUM INTERNATIONAL LIMITED (GB) 2022-06-21 US disclosed
US-20220169947-A1 High Viscosity Index Comb Polymer Viscosity Modifiers and Methods of Modifying Lubricant Viscosity Using Same INFINEUM INTERNATIONAL LIMITED (GB) 2022-06-02 US disclosed
US-20210189281-A1 High Viscosity Index Comb Polymer Viscosity Modifiers and Methods of Modifying Lubricant Viscosity Using Same lnfineum International Limited (GB) 2021-06-24 US disclosed
EP-3839017-A1 HIGH VISCOSITY INDEX COMB POLYMER VISCOSITY MODIFIERS AND METHODS OF MODIFYING LUBRICANT VISCOSITY USING SAME Infineum International Limited (GB) 2021-06-23 EP disclosed
EP-3839019-A1 HIGH VISCOSITY INDEX COMB POLYMER VISCOSITY MODIFIERS AND METHODS OF MODIFYING LUBRICANT VISCOSITY USING SAME Infineum International Limited (GB) 2021-06-23 EP disclosed
EP-3839018-A1 HIGH VISCOSITY INDEX COMB POLYMER VISCOSITY MODIFIERS AND METHODS OF MODIFYING LUBRICANT VISCOSITY USING SAME Infineum International Limited (GB) 2021-06-23 EP disclosed
CN-112980542-A High viscosity index comb polymer viscosity modifiers and methods of using the same to modify lubricant viscosity 英菲诺姆国际有限公司 2021-06-18 CN disclosed
CN-112980549-A High viscosity index comb polymer viscosity modifiers and methods of using the same to modify lubricant viscosity 英菲诺姆国际有限公司 2021-06-18 CN disclosed
CN-112980543-A High viscosity index comb polymer viscosity modifiers and methods of using the same to modify lubricant viscosity 英菲诺姆国际有限公司 2021-06-18 CN disclosed
US-20210179960-A1 High Viscosity Index Comb Copolymer Viscosity Modifiers and Methods of Modify Lubricant Viscosity Using Same INFINEUM INTERNATIONAL LIMITED (GB) 2021-06-17 US disclosed
US-20210179760-A1 High Viscosity Index Comb Polymer Viscosity Modifiers and Methods of Modifying Lubricant Viscosity Using Same INFINEUM INTERNATIONAL LIMITED (GB) 2021-06-17 US disclosed
US-20210179961-A1 High Viscosity Index Comb Copolymer Viscosity Modifiers and Methods of Modifying Lubricant Viscosity Using Same INFINEUM INTERNATIONAL LIMITED (GB) 2021-06-17 US disclosed
US-20210179965-A1 High Viscosity Index Comb Copolymer Viscosity Modifiers and Methods of Modifying Lubricant Viscosity Using Same INFINEUM INTERNATIONAL LIMITED (GB) 2021-06-17 US disclosed