SCHEMBL23498015

SCHEMBL23498015

CC(C)C(NC(=O)CCOCCOCCOCCN=[N+]=[N-])C(=O)NC(CCCNC(N)=O)C(=O)Nc1ccc(COC(=O)Oc2ccc([N+](=O)[O-])cc2)cc1

nearest known ligand 0.39

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ HTR2A P28223 1/20 0.39
▸ FURIN P09958 10/20 0.37
▸ MAP1LC3B Q9GZQ8 2/20 0.36
▸ SSTR3 P32745 1/20 0.35
▸ PDF Q9HBH1 1/20 0.35
▸ ALDH1A1 P00352 1/20 0.35
▸ MAPK1 P28482 1/20 0.35
▸ L3MBTL1 Q9Y468 1/20 0.35
▸ FOLH1 Q04609 1/20 0.34
▸ TGM2 P21980 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17490581 1.00 HTR2A (0.39) HTR2AFURINMAP1LC3BSSTR3PDF
SCHEMBL23498013 1.00 HTR2A (0.39) HTR2AFURINMAP1LC3BSSTR3PDF
SCHEMBL25976125 0.99 HTR2A (0.39) HTR2AFURINMAP1LC3BSSTR3PDF
SCHEMBL19731615 0.95 FURIN (0.39) HTR2AFURINMAP1LC3BSSTR3PDF
SCHEMBL22691442 0.95 FURIN (0.39) HTR2AFURINMAP1LC3BSSTR3PDF
SCHEMBL29649550 0.94 PDF (0.38) FURINSSTR3PDFFOLH1
SCHEMBL15223879 0.93 HTR2A (0.39) HTR2AFURINMAP1LC3BSSTR3PDF
SCHEMBL18792771 0.93 HTR2A (0.39) HTR2AFURINMAP1LC3BSSTR3PDF
SCHEMBL17312903 0.92 HTR2A (0.40) HTR2AFURINMAP1LC3BSSTR3PDF
SCHEMBL26015668 0.92 HTR2A (0.40) HTR2AFURINMAP1LC3BSSTR3PDF

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4073062-B1 FUNCTIONALIZED HETEROCYCLIC COMPOUNDS AS MODULATORS OF STIMULATOR OF INTERFERON GENES (STING) RYVU THERAPEUTICS S A (PL) 2026-04-29 — — EP disclosed
US-20230055741-A1 FUNCTIONALIZED HETEROCYCLIC COMPOUNDS AS MODULATORS OF STIMULATOR OF INTERFERON GENES (STING) Ryvu Therapeutics S.A. (PL) 2023-02-23 — — US disclosed
WO-2021116446-A1 FUNCTIONALIZED HETEROCYCLIC COMPOUNDS AS MODULATORS OF STIMULATOR OF INTERFERON GENES (STING) Ryvu Therapeutics S.A. (PL) 2021-06-17 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230055741-A1 FUNCTIONALIZED HETEROCYCLIC COMPOUNDS AS MODULATORS OF STIMULATOR OF INTERFERON GENES (STING) STING1, IRF3, CGAS HTR2A 1451/4885FURIN 1532/4885MAP1LC3B 3195/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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