Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 2/20 | 0.43 |
| ▸ | NTRK1 | P04629 | 15/20 | 0.38 |
| ▸ | JAK2 | O60674 | 12/20 | 0.38 |
| ▸ | PRCP | P42785 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23500994 | 0.87 | RIPK1 (0.43) | RIPK1NTRK1JAK2PRCPGRM5 | |
| SCHEMBL24993318 | 0.79 | RIPK1 (0.47) | RIPK1NTRK1JAK2PRCPGRM5 | |
| SCHEMBL23501030 | 0.78 | NTRK1 (0.49) | RIPK1NTRK1JAK2 | |
| SCHEMBL23501031 | 0.78 | NTRK1 (0.49) | RIPK1NTRK1JAK2 | |
| SCHEMBL24993327 | 0.77 | RIPK1 (0.41) | RIPK1NTRK1JAK2 | |
| SCHEMBL24992250 | 0.77 | RIPK1 (0.41) | RIPK1NTRK1JAK2 | |
| SCHEMBL23501013 | 0.74 | RIPK1 (0.41) | RIPK1NTRK1JAK2PRCPGRM5 | |
| SCHEMBL23501016 | 0.74 | RIPK1 (0.41) | RIPK1NTRK1JAK2PRCPGRM5 | |
| SCHEMBL21494324 | 0.70 | RIPK1 (0.44) | RIPK1NTRK1JAK2 | |
| SCHEMBL21513601 | 0.69 | RIPK1 (0.49) | RIPK1NTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021115401-A1 | FLUORINE-CONTAINING HETEROCYCLIC DERIVATIVES WITH MACROCYCLIC STRUCTURE AND USE THEREOF | 成都倍特药业股份有限公司 | 2021-06-17 | — | — | WO | disclosed |