Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 20/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.31 |
| ▸ | MYLK4 | Q86YV6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23501406 | 0.96 | ROCK2 (0.36) | ROCK2ROCK1MYLK4 | |
| SCHEMBL23927627 | 0.90 | ROCK2 (0.39) | ROCK2ROCK1MYLK4 | |
| SCHEMBL23927718 | 0.85 | ROCK2 (0.43) | ROCK2ROCK1MYLK4 | |
| SCHEMBL23501373 | 0.85 | ROCK2 (0.38) | ROCK2ROCK1MYLK4 | |
| SCHEMBL23501428 | 0.84 | ROCK2 (0.39) | ROCK2ROCK1MYLK4 | |
| SCHEMBL23927592 | 0.81 | ROCK2 (0.38) | ROCK2ROCK1MYLK4 | |
| SCHEMBL23927613 | 0.81 | ROCK2 (0.38) | ROCK2ROCK1MYLK4 | |
| SCHEMBL23521644 | 0.80 | ROCK2 (0.36) | ROCK2 | |
| SCHEMBL23522325 | 0.77 | ROCK2 (0.51) | ROCK2ROCK1MYLK4 | |
| SCHEMBL30003557 | 0.75 | ROCK2 (0.52) | ROCK2ROCK1MYLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021115495-A1 | SMALL-MOLECULE SULFUR-CONTAINING HETEROCYCLIC COMPOUND | 维眸生物科技（上海）有限公司 | 2021-06-17 | — | — | WO | disclosed |