Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.38 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.37 |
| ▸ | CACNA1H | O95180 | 4/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.36 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31364788 | 1.00 | ATM (0.48) | ATMCYP11B1CYP11B2HIF1ACYP2A6 | |
| SCHEMBL23501701 | 0.89 | ATM (0.39) | ATMCYP11B1CYP11B2HIF1ACYP2A6 | |
| SCHEMBL31359370 | 0.87 | ATM (0.46) | ATMCYP11B1CYP11B2HIF1ACYP2A6 | |
| SCHEMBL23501627 | 0.87 | ATM (0.46) | ATMCYP11B1CYP11B2HIF1ACYP2A6 | |
| SCHEMBL23501647 | 0.85 | HCAR2 (0.44) | ALDH1A1ABHD6 | |
| SCHEMBL29933977 | 0.85 | HCAR2 (0.44) | ALDH1A1ABHD6 | |
| SCHEMBL25624678 | 0.82 | ATM (0.51) | ATMCYP11B1CYP11B2CYP2A6GRM5 | |
| SCHEMBL31364792 | 0.81 | ATM (0.44) | ATMCYP11B1CYP11B2HIF1ACYP2A6 | |
| SCHEMBL23501656 | 0.81 | ATM (0.44) | ATMCYP11B1CYP11B2HIF1ACYP2A6 | |
| SCHEMBL17572997 | 0.78 | DYRK1A (0.48) | ATMEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115315421-A | Compounds and compositions as PDGF receptor kinase inhibitors | 日本新药株式会社 | 2022-11-08 | — | — | CN | disclosed |
| WO-2021117846-A1 | COMPOUND SERVING AS PDGF RECEPTOR KINASE INHIBITOR, AND COMPOSITION | 日本新薬株式会社 | 2021-06-17 | — | — | WO | disclosed |