Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.40 |
| ▸ | CACNA1H | O95180 | 3/20 | 0.39 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.39 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 2/20 | 0.37 |
| ▸ | TRPC6 | Q9Y210 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23501656 | 1.00 | ATM (0.44) | ATMGRM5HIF1AGPR88CACNA1H | |
| SCHEMBL29933848 | 0.86 | MEN1 (0.43) | GPR88CACNA1H | |
| SCHEMBL23501672 | 0.86 | MEN1 (0.43) | GPR88CACNA1H | |
| SCHEMBL28274110 | 0.85 | ATM (0.50) | ATMGRM5HIF1AP2RX3SIRT2 | |
| SCHEMBL2195576 | 0.82 | PARP10 (0.47) | ATMGRM5HIF1ASIRT2SIRT1 | |
| SCHEMBL31364788 | 0.81 | ATM (0.48) | ATMGRM5HIF1ACACNA1HP2RX3 | |
| SCHEMBL23501611 | 0.81 | ATM (0.48) | ATMGRM5HIF1ACACNA1HP2RX3 | |
| SCHEMBL23167202 | 0.77 | ATM (0.56) | ATMGRM5HIF1AP2RX3SIRT2 | |
| SCHEMBL16319115 | 0.74 | ATM (0.53) | ATMGRM5P2RX3SIRT2SIRT1 | |
| SCHEMBL31287098 | 0.74 | ATM (0.53) | ATMGRM5SIRT2SIRT1SIRT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115315421-B | Compounds and compositions as PDGF receptor kinase inhibitors | 日本新药株式会社 | 2024-12-03 | — | — | CN | disclosed |