Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | CCR5 | P51681 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31364809 | 1.00 | PKM (0.52) | PKMSMN1; SMN2MAPTLMNAL3MBTL1 | |
| SCHEMBL29933845 | 1.00 | PKM (0.52) | PKMSMN1; SMN2MAPTLMNAL3MBTL1 | |
| SCHEMBL31359391 | 0.88 | PKM (0.51) | PKMSMN1; SMN2MAPTHTTPOLB | |
| SCHEMBL28884605 | 0.83 | MAPT (0.46) | PKMSMN1; SMN2MAPTLMNAL3MBTL1 | |
| SCHEMBL31359395 | 0.81 | CYP11B1 (0.54) | MAPTLMNAL3MBTL1RAB9AHTT | |
| SCHEMBL29933942 | 0.81 | CYP11B1 (0.54) | MAPTLMNAL3MBTL1RAB9AHTT | |
| SCHEMBL23501599 | 0.81 | CYP11B1 (0.54) | MAPTLMNAL3MBTL1RAB9AHTT | |
| SCHEMBL22169882 | 0.79 | MAPT (0.51) | SMN1; SMN2MAPTLMNAL3MBTL1RAB9A | |
| SCHEMBL23501655 | 0.79 | HDAC8 (0.48) | PKMSMN1; SMN2MAPTL3MBTL1HTT | |
| SCHEMBL29934010 | 0.79 | HDAC8 (0.48) | PKMSMN1; SMN2MAPTL3MBTL1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115315421-A | Compounds and compositions as PDGF receptor kinase inhibitors | 日本新药株式会社 | 2022-11-08 | — | — | CN | disclosed |
| WO-2021117846-A1 | COMPOUND SERVING AS PDGF RECEPTOR KINASE INHIBITOR, AND COMPOSITION | 日本新薬株式会社 | 2021-06-17 | — | — | WO | disclosed |