SCHEMBL23504

SCHEMBL23504

CCC(C)(C)NC(=O)O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29665190 0.80 HPGD (0.37)
SCHEMBL29665186 0.80 HPGD (0.37)
SCHEMBL12175396 0.80 POLB (0.42)
SCHEMBL11128751 0.80 EPHX1 (0.47)
SCHEMBL2820709 0.80 EPHX1 (0.57)
SCHEMBL16391286 0.79 EPHX1 (0.42)
SCHEMBL6729367 0.79 ALDH1A1 (0.59)
SCHEMBL8155896 0.78
SCHEMBL2490315 0.78
SCHEMBL4722962 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3715346-B1 THIAZOLYL-CONTAINING COMPOUNDS FOR TREATING PROLIFERATIVE DISEASES DANA FARBER CANCER INST INC (US) 2024-01-03 EP claimed
EP-3606528-B1 TRICYCLIC COMPOUNDS AS GLYCOGEN SYNTHASE KINASE 3 (GSK3) INHIBITORS AND USES THEREOF BROAD INST INC (US) 2023-10-18 EP claimed
EP-3291676-B1 MITRAGYNINE ANALOGS AND USES THEREOF MEMORIAL SLOAN KETTERING CANCER CENTER (US) 2022-08-17 EP claimed
EP-3172213-B1 MACROCYCLIC KINASE INHIBITORS AND USES THEREOF DANA FARBER CANCER INST INC (US) 2021-09-22 EP claimed
EP-3092220-B1 VITAMIN C PRODRUGS AND USES THEREOF UNIV FLORIDA (US) 2021-01-20 EP claimed
EP-3171874-B1 IMIDAZOLYL KINASE INHIBITORS AND USES THEREOF DANA FARBER CANCER INST INC (US) 2020-11-18 EP claimed
EP-2016044-B1 PENTACYCLINE DERIVATIVES FOR THE TREATMENT OF INFECTIONS HARVARD COLLEGE (US) 2020-06-10 EP claimed
EP-3209648-B1 THIAZOLYL-CONTAINING COMPOUNDS FOR TREATING PROLIFERATIVE DISEASES DANA FARBER CANCER INST INC (US) 2020-03-11 EP claimed
EP-2550285-B1 TRIOXACARCINS AND USES THEREOF HARVARD COLLEGE (US) 2017-07-19 EP claimed
US-4958018-A REACTING A 3-HALOMETHYL-3-CEPHEM WITH A LEAD REDUCING AGENT OTSUKA KAGAKU KABUSHIKI KAISHA (JP) 1990-09-18 US claimed
US-12215100-B2 Anticancer compounds PHARMA MAR, S.A. (ES) 2025-02-04 US disclosed
US-20240294506-A1 CDK2 INHIBITORS PFIZER INC. (US) 2024-09-05 US disclosed
EP-3898613-B1 ANTICANCER COMPOUNDS PHARMA MAR SA (ES) 2023-08-09 EP disclosed
US-11718603-B2 CDK2 inhibitors PFIZER INC. (US) 2023-08-08 US disclosed
WO-2023072096-A1 TETRAHYDROFURAN-CONTAINING POLYCYCLIC DERIVATIVE AND PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, PREPARATION METHOD THEREFOR AND USE THEREOF 优领医药科技(香港)有限公司 2023-05-04 WO disclosed
EP-0149558-B1 HIGH EFFICIENCY POLYMERIZATION CATALYST COMPONENT FOR USE IN THE POLYMERIZATION OF PROPYLENE AND HIGHER ALPHA-OLEFINS EXXON RESEARCH AND ENGINEERING COMPANY (US) 1989-03-15 EP disclosed
US-4677088-A COORDINATION CATALYST ORGANOALUMINUM COMPOUND AND LEWIS BASE EXXON CHEMICAL PATENTS INC. (US) 1987-06-30 US disclosed
US-4587353-A Process for producing N-chlorosulfenyl compounds CIBA-GEIGY CORPORATION (US) 1986-05-06 US disclosed
EP-0149558-A2 High efficiency polymerization catalyst component for use in the polymerization of propylene and higher alpha-olefins EXXON RESEARCH AND ENGINEERING COMPANY (US) 1985-07-24 EP disclosed
US-4525467-A MIXED ALUMINUM HYDROCARBYL-LEWIS BASE COORDINATION CATALYST EXXON RESEARCH & ENGINEERING CO. (US) 1985-06-25 US disclosed