Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18971164 | 0.78 | PSEN1 (0.38) | RIPK1 | |
| SCHEMBL18971166 | 0.78 | PSEN1 (0.38) | RIPK1 | |
| SCHEMBL20159585 | 0.78 | PSEN1 (0.34) | RIPK1 | |
| SCHEMBL21050393 | 0.78 | PSEN1 (0.38) | RIPK1 | |
| SCHEMBL18952804 | 0.78 | PSEN1 (0.38) | RIPK1 | |
| SCHEMBL23504787 | 0.78 | — | — | |
| SCHEMBL20159352 | 0.73 | — | — | |
| SCHEMBL24921382 | 0.70 | CHRM3 (0.35) | RIPK1 | |
| SCHEMBL2276427 | 0.70 | RIPK1 (0.42) | RIPK1 | |
| SCHEMBL16578759 | 0.67 | KHK (0.35) | RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3538516-B1 | PHENOXYTRIAZOLES | HOFFMANN LA ROCHE (CH) | 2021-06-16 | — | — | EP | disclosed |