Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLP1R | P43220 | 8/20 | 0.58 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.47 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.44 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.44 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.44 |
| ▸ | CASP2 | P42575 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 4/20 | 0.43 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.43 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.43 |
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20976640 | 0.92 | GLP1R (0.50) | GLP1RNOD1GNAI3GNAO1GNAI1 | |
| SCHEMBL17189428 | 0.91 | GLP1R (0.70) | GLP1RNOD1GNAI3GNAO1GNAI1 | |
| SCHEMBL19049679 | 0.90 | GLP1R (0.52) | GLP1RNOD1 | |
| SCHEMBL13640888 | 0.87 | GLP1R (0.43) | GLP1RGNAI3GNAO1GNAI1FAAH | |
| SCHEMBL22646981 | 0.87 | NOD1 (0.59) | NOD1GNAI3GNAO1GNAI1CASP2 | |
| SCHEMBL17922790 | 0.86 | GLP1R (0.58) | GLP1RNOD1GNAI3GNAO1GNAI1 | |
| SCHEMBL12982269 | 0.86 | GLP1R (0.60) | GLP1RNOD1CASP2FAAHSLC6A5 | |
| SCHEMBL12982128 | 0.86 | GLP1R (0.60) | GLP1RNOD1CASP2FAAHSLC6A5 | |
| SCHEMBL17922791 | 0.85 | GLP1R (0.60) | GLP1RNOD1GNAI3GNAO1GNAI1 | |
| SCHEMBL14530622 | 0.85 | GLP1R (0.42) | GLP1RGNAI3GNAO1GNAI1DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2932981-B1 | Albumin-binding derivatives of GLP-1 | NOVO NORDISK AS (DK) | 2021-06-16 | — | — | EP | disclosed |