Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 4/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.36 |
| ▸ | WDR5 | P61964 | 2/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 2/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29965264 | 0.91 | P2RX7 (0.37) | CNR2TP53THRBCNR1ALDH1A1 | |
| SCHEMBL21922514 | 0.91 | P2RX7 (0.37) | CNR2TP53THRBCNR1ALDH1A1 | |
| SCHEMBL20143007 | 0.90 | CNR2 (0.39) | PKMCNR2TP53THRBCNR1 | |
| SCHEMBL20154267 | 0.90 | CNR2 (0.39) | PKMCNR2TP53THRBCNR1 | |
| SCHEMBL30071194 | 0.90 | CNR2 (0.39) | PKMCNR2TP53THRBCNR1 | |
| SCHEMBL29965225 | 0.87 | CNR2 (0.38) | CNR2CNR1ALDH1A1P2RX7TRPV1 | |
| SCHEMBL21875796 | 0.87 | CNR2 (0.38) | CNR2CNR1ALDH1A1P2RX7TRPV1 | |
| SCHEMBL20621805 | 0.87 | P2RX7 (0.38) | PKMCNR2TP53CNR1ALDH1A1 | |
| SCHEMBL21875798 | 0.87 | P2RX7 (0.38) | PKMCNR2TP53CNR1ALDH1A1 | |
| SCHEMBL29438262 | 0.87 | P2RX7 (0.38) | PKMCNR2TP53CNR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3538512-B1 | NEW ANTHELMINTIC QUINOLINE-3-CARBOXAMIDE DERIVATIVES | BAYER ANIMAL HEALTH GMBH (DE) | 2021-06-16 | — | — | EP | disclosed |