Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13028893 | 0.79 | TRPA1 (0.33) | LATS1LATS2 | |
| SCHEMBL13848825 | 0.72 | TSHR (0.39) | LATS1LATS2 | |
| SCHEMBL280624 | 0.72 | TSHR (0.39) | LATS1LATS2 | |
| SCHEMBL12512791 | 0.72 | TSHR (0.39) | LATS1LATS2 | |
| SCHEMBL2892375 | 0.71 | GAA (0.41) | LATS1LATS2 | |
| SCHEMBL2737302 | 0.70 | RPS6KA3 (0.43) | LATS1LATS2 | |
| SCHEMBL19133216 | 0.70 | CYP1A2 (0.37) | LATS1LATS2 | |
| SCHEMBL22043381 | 0.69 | PRKCH (0.33) | LATS1LATS2 | |
| SCHEMBL20693003 | 0.69 | TRPA1 (0.36) | LATS1LATS2 | |
| SCHEMBL19173619 | 0.68 | KDM4E (0.38) | LATS1LATS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021115286-A1 | SIX-MEMBERED AND FIVE-MEMBERED AROMATIC RING DERIVATIVE CONTAINING NITROGEN HETEROATOMS WHICH CAN BE USED AS SHP2 INHIBITOR | 成都倍特药业股份有限公司 | 2021-06-17 | — | — | WO | disclosed |