Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | AKT1 | P31749 | 3/20 | 0.52 |
| ▸ | AKT2 | P31751 | 3/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | USP7 | Q93009 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23509740 | 1.00 | MAPT (0.53) | MAPTTP53ALDH1A1NPC1RAB9A | |
| SCHEMBL23509706 | 0.93 | AKT1 (0.57) | MAPTTP53ALDH1A1NPC1RAB9A | |
| SCHEMBL23509788 | 0.93 | AKT1 (0.57) | MAPTTP53ALDH1A1NPC1RAB9A | |
| SCHEMBL23509697 | 0.93 | AKT1 (0.57) | MAPTTP53ALDH1A1NPC1RAB9A | |
| SCHEMBL23509738 | 0.92 | AKT1 (0.56) | MAPTTP53ALDH1A1NPC1RAB9A | |
| SCHEMBL23509647 | 0.92 | AKT1 (0.56) | MAPTTP53ALDH1A1NPC1RAB9A | |
| SCHEMBL23509742 | 0.92 | AKT1 (0.56) | MAPTTP53ALDH1A1NPC1RAB9A | |
| SCHEMBL23509799 | 0.92 | AKT1 (0.56) | MAPTTP53ALDH1A1NPC1RAB9A | |
| SCHEMBL23509623 | 0.92 | AKT1 (0.56) | MAPTTP53ALDH1A1NPC1RAB9A | |
| SCHEMBL25790017 | 0.92 | ALDH1A1 (0.59) | MAPTTP53ALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021114801-A1 | IMIDAZOPYRIDINE-BASED ARYLAMINE COMPOUND AND USE THEREOF | 广东阿格蕾雅光电材料有限公司 | 2021-06-17 | — | — | WO | disclosed |