Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 5/20 | 0.38 |
| ▸ | AKT2 | P31751 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.32 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.32 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23509727 | 0.96 | AKT1 (0.38) | AKT1AKT2NPC1RAB9AATM | |
| SCHEMBL23509711 | 0.95 | AKT1 (0.42) | AKT1AKT2NPC1RAB9AATM | |
| SCHEMBL23509624 | 0.95 | AKT1 (0.42) | AKT1AKT2NPC1RAB9AATM | |
| SCHEMBL23509734 | 0.91 | AKT1 (0.38) | AKT1AKT2NPC1RAB9AATM | |
| SCHEMBL22673682 | 0.90 | AKT1 (0.43) | AKT1AKT2NPC1RAB9AATM | |
| SCHEMBL23509625 | 0.90 | AKT1 (0.42) | AKT1AKT2NPC1RAB9AATM | |
| SCHEMBL23509716 | 0.90 | AKT1 (0.42) | AKT1AKT2NPC1RAB9AATM | |
| SCHEMBL22673680 | 0.89 | AKT1 (0.44) | AKT1AKT2NPC1RAB9AATM | |
| SCHEMBL23509791 | 0.89 | AKT1 (0.43) | AKT1AKT2NPC1RAB9AATM | |
| SCHEMBL23509743 | 0.89 | AKT1 (0.43) | AKT1AKT2NPC1RAB9AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021114801-A1 | IMIDAZOPYRIDINE-BASED ARYLAMINE COMPOUND AND USE THEREOF | 广东阿格蕾雅光电材料有限公司 | 2021-06-17 | — | — | WO | disclosed |