Sugi Predict

Sugi Predict / Compounds / SCHEMBL23509624

SCHEMBL23509624

SCHEMBL23509624

c1ccc(-c2nc3ccccn3c2-c2ccc(N(c3ccccc3)c3ccc(-c4ccc5c6ccccc6n(-c6ccccc6)c5c4)cc3)cc2)cc1

nearest known ligand 0.42

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ AKT1 P31749 10/20 0.42
▸ AKT2 P31751 10/20 0.42
▸ NPC1 O15118 2/20 0.37
▸ RAB9A P51151 2/20 0.37
▸ ATM Q13315 2/20 0.35
▸ KDM4E B2RXH2 1/20 0.35
▸ L3MBTL1 Q9Y468 1/20 0.35
▸ USP7 Q93009 1/20 0.35
▸ ADRA1B P35368 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23509711 1.00 AKT1 (0.42) AKT1AKT2NPC1RAB9AATM
SCHEMBL23509679 0.95 AKT1 (0.38) AKT1AKT2NPC1RAB9AATM
SCHEMBL23509727 0.95 AKT1 (0.38) AKT1AKT2NPC1RAB9AATM
SCHEMBL23509716 0.94 AKT1 (0.42) AKT1AKT2NPC1RAB9AATM
SCHEMBL23509625 0.94 AKT1 (0.42) AKT1AKT2NPC1RAB9AATM
SCHEMBL23509790 0.92 AKT1 (0.47) AKT1AKT2NPC1RAB9AATM
SCHEMBL23509744 0.92 AKT1 (0.47) AKT1AKT2NPC1RAB9AATM
SCHEMBL23509791 0.91 AKT1 (0.43) AKT1AKT2NPC1RAB9AATM
SCHEMBL23509743 0.91 AKT1 (0.43) AKT1AKT2NPC1RAB9AATM
SCHEMBL24479219 0.91 AKT1 (0.46) AKT1AKT2NPC1RAB9AATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021114801-A1 IMIDAZOPYRIDINE-BASED ARYLAMINE COMPOUND AND USE THEREOF 广东阿格蕾雅光电材料有限公司 2021-06-17 — — WO disclosed
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