Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 3/20 | 0.47 |
| ▸ | AKT2 | P31751 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | USP7 | Q93009 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.37 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.36 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23509744 | 1.00 | AKT1 (0.47) | AKT1AKT2NPC1RAB9AUSP7 | |
| SCHEMBL23509743 | 0.93 | AKT1 (0.43) | AKT1AKT2NPC1RAB9AUSP7 | |
| SCHEMBL23509791 | 0.93 | AKT1 (0.43) | AKT1AKT2NPC1RAB9AUSP7 | |
| SCHEMBL23509724 | 0.92 | AKT1 (0.41) | AKT1AKT2NPC1RAB9AUSP7 | |
| SCHEMBL9888855 | 0.92 | AKT1 (0.53) | AKT1AKT2NPC1RAB9AUSP7 | |
| SCHEMBL9888885 | 0.92 | AKT1 (0.53) | AKT1AKT2NPC1RAB9AUSP7 | |
| SCHEMBL23509624 | 0.92 | AKT1 (0.42) | AKT1AKT2NPC1RAB9AUSP7 | |
| SCHEMBL23509711 | 0.92 | AKT1 (0.42) | AKT1AKT2NPC1RAB9AUSP7 | |
| SCHEMBL23509716 | 0.92 | AKT1 (0.42) | AKT1AKT2NPC1RAB9AUSP7 | |
| SCHEMBL23509625 | 0.92 | AKT1 (0.42) | AKT1AKT2NPC1RAB9AUSP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021114801-A1 | IMIDAZOPYRIDINE-BASED ARYLAMINE COMPOUND AND USE THEREOF | 广东阿格蕾雅光电材料有限公司 | 2021-06-17 | — | — | WO | disclosed |