SCHEMBL235129

SCHEMBL235129

Cc1ccc(C(c2ccccc2)(c2ccc(C)cc2)[C@]2(O)C[C@H](n3ccc(NC(=O)c4ccccc4)nc3=O)O[C@@H]2CO)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABL1 P00519 1/20 0.56
RIN1 Q13671 1/20 0.56
POLB P06746 1/20 0.52
P2RY6 Q15077 2/20 0.41
P2RY14 Q15391 2/20 0.41
NT5E P21589 1/20 0.41
NPC1 O15118 4/20 0.35
RAB9A P51151 4/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
L3MBTL1 Q9Y468 1/20 0.34
MAP3K5 Q99683 1/20 0.33
HTR1A P08908 2/20 0.33
HTR1F P30939 2/20 0.33
HTR1D P28221 1/20 0.33
HTR1B P28222 1/20 0.33
MAPT P10636 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
LMNA P02545 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL235128 0.91 ABL1 (0.56) ABL1RIN1POLBP2RY6P2RY14
SCHEMBL9060202 0.82 ABL1 (0.61) ABL1RIN1POLBP2RY6P2RY14
SCHEMBL20974963 0.77 ABL1 (0.59) ABL1RIN1POLBP2RY6P2RY14
SCHEMBL15090413 0.74 ABL1 (0.70) ABL1RIN1POLBP2RY6P2RY14
SCHEMBL14980414 0.74 ABL1 (0.70) ABL1RIN1POLBP2RY6P2RY14
SCHEMBL13557957 0.73 ABL1 (0.75) ABL1RIN1POLBP2RY6P2RY14
SCHEMBL6305884 0.73 ABL1 (0.58) ABL1RIN1POLBP2RY6P2RY14
SCHEMBL6306039 0.73 ABL1 (0.58) ABL1RIN1POLBP2RY6P2RY14
SCHEMBL1527090 0.73 POLB (0.57) ABL1RIN1POLBP2RY6P2RY14
SCHEMBL13170024 0.73 ABL1 (1.00) ABL1RIN1POLBP2RY6P2RY14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE48909-E1 Tagged oligonucleotides and their use in nucleic acid amplification methods GEN-PROBE INCORPORATED (US) 2022-02-01 US disclosed
US-11198913-B2 Compositions, kits and related methods for the detection and/or monitoring of Listeria GEN-PROBE INCORPORATED (US) 2021-12-14 US disclosed
US-20210024982-A1 INACTIVATABLE TARGET CAPTURE OLIGOMERS FOR USE IN THE SELECTIVE HYBRIDIZATION AND CAPTURE OF TARGET NUCLEIC ACID SEQUENCES GEN-PROBE INCORPORATED (US) 2021-01-28 US disclosed
US-10829801-B2 Inactivatable target capture oligomers for use in the selective hybridization and capture of target nucleic acid sequences GEN-PROBE INCORPORATED (US) 2020-11-10 US disclosed
US-10711295-B2 Compositions, kits and related methods for the detection and/or monitoring of salmonella GEN-PROBE INCORPORATED (US) 2020-07-14 US disclosed
US-10626466-B2 Compositions, kits and related methods for the detection and/or monitoring of Pseudomonas aeruginosa GEN-PROBE INCORPORATED (US) 2020-04-21 US disclosed
US-20200048684-A1 COMPOSITIONS, KITS AND RELATED METHODS FOR THE DETECTION AND/OR MONITORING OF LISTERIA BANK OF AMERICA, N.A., AS COLLATERAL AGENT 2020-02-13 US disclosed
US-10316352-B2 Methods of capturing a target nucleic acid for amplification and detection using an inactivatable target capture oligomer GEN-PROBE INCORPORATED (US) 2019-06-11 US disclosed
US-20190136293-A1 Compositions, Kits and Related Methods for the Detection and/or Monitoring of Salmonella GEN-PROBE INCORPORATED (US) 2019-05-09 US disclosed
US-10240185-B2 Compositions, kits and related methods for the detection and/or monitoring of Salmonella GEN-PROBE INCORPORATED (US) 2019-03-26 US disclosed
WO-2008108843-A2 METHODS AND KITS FOR AMPLIFYING DNA GEN-PROBE INCORPORATED (US) 2008-09-12 WO disclosed
EP-1945821-A1 TAGGED OLIGONUCLEOTIDES AND THEIR USE IN NUCLEIC ACID AMPLIFICATION METHODS GEN-PROBE INCORPORATED (US) 2008-07-23 EP disclosed
US-7374885-B2 Single-primer nucleic acid amplification methods GEN-PROBE INCORPORATED (US) 2008-05-20 US disclosed
US-20070299254-A1 Kits for Performing Amplification Reactions GEN-PROBE INCORPORATED (US) 2007-12-27 US disclosed
WO-2007146154-A1 TAGGED OLIGONUCLEOTIDES AND THEIR USE IN NUCLEIC ACID AMPLIFICATION METHODS GEN-PROBE INCORPORATED (US) 2007-12-21 WO disclosed
US-20070281317-A1 Tagged oligonucleotides and their use in nucleic acid amplification methods GEN-PROBE INCORPORATED (US) 2007-12-06 US disclosed
US-20070202523-A1 METHODS AND KITS FOR AMPLIFYING DNA GEN-PROBE INCORPORATED 2007-08-30 US disclosed
EP-1786916-A2 SINGLE-PRIMER NUCLEIC ACID AMPLIFICATION METHODS GEN-PROBE INCORPORATED (US) 2007-05-23 EP disclosed
WO-2006026388-A2 SINGLE-PRIMER NUCLEIC ACID AMPLIFICATION METHODS GEN-PROBE INCORPORATED (US) 2006-03-09 WO disclosed
US-20060046265-A1 Single-primer nucleic acid amplification methods GEN-PROBE INCORPORATED (US) 2006-03-02 US disclosed