SCHEMBL9060202

SCHEMBL9060202

CC(C)(C)[Si](C)(C)[C@]1(O)C[C@H](n2ccc(NC(=O)c3ccccc3)nc2=O)O[C@@H]1CO

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABL1 P00519 1/20 0.61
RIN1 Q13671 1/20 0.61
POLB P06746 1/20 0.56
P2RY6 Q15077 2/20 0.44
P2RY14 Q15391 2/20 0.44
NT5E P21589 1/20 0.44
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
MAP3K5 Q99683 1/20 0.37
CYP2C9 P11712 1/20 0.35
MAPT P10636 1/20 0.34
HTT P42858 1/20 0.34
NPC1 O15118 3/20 0.33
RAB9A P51151 3/20 0.33
ALDH1A1 P00352 1/20 0.33
HTR1A P08908 1/20 0.33
HTR1D P28221 1/20 0.33
HTR1B P28222 1/20 0.33
HTR1F P30939 1/20 0.33
LMNA P02545 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20974963 0.82 ABL1 (0.59) ABL1RIN1POLBP2RY6P2RY14
SCHEMBL235129 0.82 ABL1 (0.56) ABL1RIN1POLBP2RY6P2RY14
SCHEMBL29703072 0.81 ABL1 (0.41) ABL1RIN1POLBP2RY6P2RY14
SCHEMBL235128 0.80 ABL1 (0.56) ABL1RIN1POLBP2RY6P2RY14
SCHEMBL26136467 0.77 ABL1 (0.58) ABL1RIN1POLBP2RY6P2RY14
SCHEMBL13557957 0.77 ABL1 (0.75) ABL1RIN1POLBP2RY6P2RY14
SCHEMBL6305884 0.76 ABL1 (0.58) ABL1RIN1POLBP2RY6P2RY14
SCHEMBL6306039 0.76 ABL1 (0.58) ABL1RIN1POLBP2RY6P2RY14
SCHEMBL3485953 0.76 ABL1 (1.00) ABL1RIN1POLBP2RY6P2RY14
SCHEMBL13170024 0.76 ABL1 (1.00) ABL1RIN1POLBP2RY6P2RY14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1996016073-A2 CODON AMIDITES AND METHOD OF USING THEM TO PRODUCE OLIGONUCLEOTIDES AND MUTAGENESIS LIBRARIES TERRAPIN TECHNOLOGIES, INC. (US) 1996-05-30 WO disclosed