Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.47 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.43 |
| ▸ | CHUK | O15111 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.35 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | MERTK | Q12866 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23500253 | 0.88 | KCNH2 (0.45) | KCNH2NUDT1CHUK | |
| SCHEMBL23500988 | 0.83 | KCNH2 (0.41) | KCNH2CHUK | |
| SCHEMBL23500883 | 0.83 | KCNH2 (0.41) | KCNH2CHUK | |
| SCHEMBL23500518 | 0.82 | ILK (0.44) | KCNH2 | |
| SCHEMBL23501099 | 0.81 | KCNH2 (0.39) | KCNH2 | |
| SCHEMBL23501101 | 0.81 | KCNH2 (0.39) | KCNH2 | |
| SCHEMBL23513823 | 0.77 | APP (0.46) | KCNH2CHUKHRH4PDE4BCHRM4 | |
| SCHEMBL23513920 | 0.74 | KCNH2 (0.53) | KCNH2NUDT1CHUKPDE4BCHRM4 | |
| SCHEMBL29653649 | 0.72 | KCNH2 (0.43) | KCNH2CHUKAPP | |
| SCHEMBL23513867 | 0.70 | APP (0.50) | APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021114691-A1 | NITROGEN-CONTAINING RING-FUSED COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2021-06-17 | — | — | WO | disclosed |