Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | STAT3 | P40763 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | DHFR | P00374 | 1/20 | 0.44 |
| ▸ | PPIA | P62937 | 1/20 | 0.44 |
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | PTGER1 | P34995 | 6/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | FYN | P06241 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30345720 | 0.86 | DHFR (0.48) | ENPP2DHFRPPIAMAP4K4PTGER1 | |
| SCHEMBL23501727 | 0.86 | DHFR (0.48) | ENPP2DHFRPPIAMAP4K4PTGER1 | |
| SCHEMBL22239416 | 0.80 | FYN (0.56) | SMN1; SMN2MAPTLMNAMAP4K4RAB9A | |
| SCHEMBL23501775 | 0.79 | MAP4K4 (0.49) | MCL1PPIAMAP4K4PTGER1CYP2C9 | |
| SCHEMBL7489944 | 0.77 | DHFR (0.49) | MAPTL3MBTL1KDM4EHPGDMAPK1 | |
| SCHEMBL23501776 | 0.76 | KMT2A (0.47) | SMN1; SMN2MAPTLMNAKDM4EHPGD | |
| SCHEMBL34467306 | 0.75 | EGLN1 (0.58) | MAPTL3MBTL1KDM4E | |
| SCHEMBL23501771 | 0.75 | EGLN1 (0.58) | MAPTL3MBTL1KDM4E | |
| SCHEMBL23319645 | 0.74 | ESR2 (0.54) | SMN1; SMN2MAPTLMNAMAP4K4RAB9A | |
| SCHEMBL16926498 | 0.73 | GCK (0.55) | SMN1; SMN2HTTSTAT3MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021117767-A1 | METHOD FOR PRODUCING NITROGEN-CONTAINING HETEROARYLCARBOXAMIDE ACETIC ACID DERIVATIVE | 田辺三菱製薬株式会社 | 2021-06-17 | — | — | WO | disclosed |