Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.52 |
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CA7 | P43166 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.50 |
| ▸ | STS | P08842 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 5/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23515189 | 0.87 | LMNA (0.54) | LMNACYP1A2CYP3A4MAOAEPHX2 | |
| SCHEMBL11756971 | 0.86 | LMNA (0.61) | LMNACYP1A2CYP3A4MAOAEPHX2 | |
| SCHEMBL26933474 | 0.85 | LMNA (0.57) | LMNACYP1A2CYP3A4MAOAEPHX2 | |
| SCHEMBL26933468 | 0.85 | LMNA (0.57) | LMNACYP1A2CYP3A4MAOAEPHX2 | |
| SCHEMBL23514842 | 0.84 | EPHX2 (0.47) | LMNACYP1A2CYP3A4MAOAEPHX2 | |
| SCHEMBL11758763 | 0.82 | PARP10 (0.59) | LMNACYP1A2CYP3A4MAOAEPHX2 | |
| SCHEMBL15994441 | 0.81 | LMNA (0.54) | LMNACYP1A2CYP3A4MAOAEPHX2 | |
| SCHEMBL3910337 | 0.81 | SCN1A (0.58) | LMNACYP1A2CYP3A4MAOAEPHX2 | |
| SCHEMBL23515035 | 0.80 | CASR (0.49) | LMNACYP1A2CYP3A4MAOAEPHX2 | |
| SCHEMBL237386 | 0.79 | LMNA (0.57) | LMNACYP1A2CYP3A4MAOAEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021115560-A1 | NEW FYN AND VEGFR2 KINASE INHIBITORS | ROTTAPHARM BIOTECH S.R.L. (IT) | 2021-06-17 | — | — | WO | disclosed |