Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 7/20 | 0.43 |
| ▸ | EDNRB | P24530 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23514968 | 0.93 | EDNRA (0.36) | EDNRAEDNRBALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL23515205 | 0.89 | EDNRA (0.44) | EDNRAEDNRBALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL23514980 | 0.83 | ALDH1A1 (0.36) | ALDH1A1MAPK1SMN1; SMN2LMNAHSP90AA1 | |
| SCHEMBL23514971 | 0.79 | EDNRA (0.39) | EDNRAEDNRBALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL25013425 | 0.78 | EDNRA (0.70) | EDNRAEDNRB | |
| SCHEMBL23514947 | 0.72 | ALDH1A1 (0.35) | EDNRAEDNRBALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL25012556 | 0.69 | EDNRA (0.52) | EDNRAEDNRB | |
| SCHEMBL23514982 | 0.68 | EDNRA (0.63) | EDNRAEDNRBSMN1; SMN2 | |
| SCHEMBL795156 | 0.67 | KMT2A (0.38) | EDNRAEDNRBALDH1A1LMNAHSP90AA1 | |
| SCHEMBL7338764 | 0.65 | EDNRA (0.84) | EDNRAEDNRBALDH1A1MAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021118826-A1 | DEUTERIUM-ENRICHED SUBSTITUTED PHENOXYPHENYL ACETIC ACIDS AND ACYLSULFONAMIDES | DHANOA DALJIT (US) | 2021-06-17 | — | — | WO | disclosed |