Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 5/20 | 0.53 |
| ▸ | PBK | Q96KB5 | 2/20 | 0.50 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.45 |
| ▸ | DPP4 | P27487 | 2/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.42 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.42 |
| ▸ | CDC42BPB | Q9Y5S2 | 3/20 | 0.42 |
| ▸ | PIM1 | P11309 | 3/20 | 0.42 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.42 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.42 |
| ▸ | KHK | P50053 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.40 |
| ▸ | CDC42BPA | Q5VT25 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16684832 | 0.84 | HRH4 (0.44) | HRH4PBKKHK | |
| SCHEMBL23515046 | 0.84 | HRH4 (0.45) | HRH4MAP4K4 | |
| SCHEMBL7008838 | 0.81 | HRH4 (0.48) | HRH4KHK | |
| Hydrochloric Acid SCHEMBL16684861 | 0.80 | HRH4 (0.47) | HRH4KHK | |
| SCHEMBL20757090 | 0.80 | HRH4 (0.47) | HRH4 | |
| SCHEMBL20756422 | 0.80 | HRH4 (0.45) | HRH4 | |
| SCHEMBL425041 | 0.79 | HRH4 (0.56) | HRH4 | |
| SCHEMBL23504190 | 0.79 | DOT1L (0.44) | HRH4PBKDOT1LROCK2ROCK1 | |
| SCHEMBL22774088 | 0.79 | DOT1L (0.44) | HRH4PBKDOT1LROCK2ROCK1 | |
| SCHEMBL25372604 | 0.79 | DOT1L (0.44) | HRH4PBKDOT1LROCK2ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021116446-A1 | FUNCTIONALIZED HETEROCYCLIC COMPOUNDS AS MODULATORS OF STIMULATOR OF INTERFERON GENES (STING) | Ryvu Therapeutics S.A. (PL) | 2021-06-17 | — | — | WO | disclosed |