Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.66 |
| ▸ | LMNA | P02545 | 3/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.66 |
| ▸ | RAB9A | P51151 | 5/20 | 0.64 |
| ▸ | NPC1 | O15118 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | ATM | Q13315 | 1/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9674665 | 0.97 | GAA (0.66) | GAAKMT2ASMN1; SMN2LMNAALDH1A1 | |
| Hydrochloric Acid SCHEMBL9674660 | 0.97 | GAA (0.66) | GAAKMT2ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL20583292 | 0.86 | GAA (0.71) | GAAKMT2ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL9795955 | 0.86 | GAA (0.71) | GAAKMT2ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL9795959 | 0.86 | GAA (0.71) | GAAKMT2ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL943308 | 0.84 | ATM (0.66) | GAAKMT2ASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL943309 | 0.84 | ATM (0.66) | GAAKMT2ASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL27178276 | 0.83 | GAA (0.86) | GAAKMT2ALMNAALDH1A1RAB9A | |
| SCHEMBL27178272 | 0.83 | GAA (0.86) | GAAKMT2ALMNAALDH1A1RAB9A | |
| Phenyl(Methyl)Semicarbazone SCHEMBL17119918 | 0.80 | ALDH1A1 (1.00) | GAAKMT2ASMN1; SMN2LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021116477-A1 | METHOD OF SUPPRESSING CANCER BY RNA m6A METHYLTRANSFERASE METTL16 INHIBITORS | CHEMESTMED LTD. (EE) | 2021-06-17 | — | — | WO | disclosed |