Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | HBB | P68871 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.52 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.52 |
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23516383 | 1.00 | CYP3A4 (0.53) | CYP3A4ALOX15TSHRMAPK1HBB | |
| SCHEMBL23516382 | 1.00 | CYP3A4 (0.53) | CYP3A4ALOX15TSHRMAPK1HBB | |
| SCHEMBL599748 | 0.89 | SLC7A5 (0.62) | CYP3A4ALOX15ALDH1A1HIF1APTGS1 | |
| SCHEMBL2779272 | 0.89 | SLC7A5 (0.62) | CYP3A4ALOX15ALDH1A1HIF1APTGS1 | |
| SCHEMBL29588290 | 0.89 | SLC7A5 (0.62) | CYP3A4ALOX15ALDH1A1HIF1APTGS1 | |
| SCHEMBL23516386 | 0.89 | CYP3A4 (0.45) | CYP3A4ALOX15TSHRMAPK1HBB | |
| SCHEMBL24947621 | 0.89 | CYP3A4 (0.45) | CYP3A4ALOX15TSHRMAPK1HBB | |
| SCHEMBL23516388 | 0.89 | CYP3A4 (0.45) | CYP3A4ALOX15TSHRMAPK1HBB | |
| SCHEMBL24947622 | 0.88 | ALDH1A1 (0.58) | CYP3A4ALOX15ALDH1A1HIF1APTGS1 | |
| SCHEMBL27310361 | 0.88 | ALDH1A1 (0.58) | CYP3A4ALOX15ALDH1A1HIF1APTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024073568-A2 | EVOLUTION OF FLUOROGENIC SENSORS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2024-04-04 | — | — | WO | disclosed |
| US-20230028318-A1 | FLUOROGENIC AMINO ACIDS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2023-01-26 | — | — | US | disclosed |
| WO-2021118727-A2 | FLUOROGENIC AMINO ACIDS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2021-06-17 | — | — | WO | disclosed |