Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 1/20 | 0.49 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.49 |
| ▸ | GPR139 | Q6DWJ6 | 3/20 | 0.49 |
| ▸ | ATM | Q13315 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | CCR2 | P41597 | 3/20 | 0.43 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30001111 | 0.89 | ITGB1 (0.49) | ITGB1ITGA5GPR139ATMMEN1 | |
| SCHEMBL23455481 | 0.89 | ITGB1 (0.49) | ITGB1ITGA5GPR139ATMMEN1 | |
| SCHEMBL30001680 | 0.89 | ITGB1 (0.49) | ITGB1ITGA5GPR139ATMMEN1 | |
| SCHEMBL23455482 | 0.89 | ITGB1 (0.49) | ITGB1ITGA5GPR139ATMMEN1 | |
| SCHEMBL23455558 | 0.85 | ITGB1 (0.44) | ITGB1ITGA5GPR139ATMMEN1 | |
| SCHEMBL30001297 | 0.85 | ITGB1 (0.44) | ITGB1ITGA5GPR139ATMMEN1 | |
| SCHEMBL23455557 | 0.85 | ITGB1 (0.44) | ITGB1ITGA5GPR139ATMMEN1 | |
| SCHEMBL23455354 | 0.85 | ITGB1 (0.47) | ITGB1ITGA5MEN1KMT2A | |
| SCHEMBL23455356 | 0.85 | ITGB1 (0.47) | ITGB1ITGA5MEN1KMT2A | |
| SCHEMBL23455443 | 0.84 | ITGB1 (0.55) | ITGB1ITGA5GPR139ATMMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021119199-A1 | ALPHA-5 BETA-1 INHIBITORS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-06-17 | — | — | WO | disclosed |