Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 6/20 | 0.44 |
| ▸ | ITGA5 | P08648 | 2/20 | 0.44 |
| ▸ | ITGA4 | P13612 | 4/20 | 0.40 |
| ▸ | ITGB7 | P26010 | 3/20 | 0.40 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | GPR139 | Q6DWJ6 | 6/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.38 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.38 |
| ▸ | ITGAL | P20701 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23455558 | 1.00 | ITGB1 (0.44) | ITGB1ITGA5ITGA4ITGB7ITGA2 | |
| SCHEMBL23455557 | 1.00 | ITGB1 (0.44) | ITGB1ITGA5ITGA4ITGB7ITGA2 | |
| SCHEMBL30001111 | 0.94 | ITGB1 (0.49) | ITGB1ITGA5ITGA4MEN1KMT2A | |
| SCHEMBL23455482 | 0.94 | ITGB1 (0.49) | ITGB1ITGA5ITGA4MEN1KMT2A | |
| SCHEMBL30001680 | 0.94 | ITGB1 (0.49) | ITGB1ITGA5ITGA4MEN1KMT2A | |
| SCHEMBL23455481 | 0.94 | ITGB1 (0.49) | ITGB1ITGA5ITGA4MEN1KMT2A | |
| SCHEMBL28958734 | 0.91 | ITGB1 (0.53) | ITGB1ITGA5ITGA4ITGB7ITGA2 | |
| SCHEMBL23455362 | 0.86 | ITGB1 (0.60) | ITGB1ITGA5MEN1KMT2AALDH1A1 | |
| SCHEMBL23455543 | 0.86 | ITGB1 (0.50) | ITGB1ITGA5ITGA4ITGB7ITGA2 | |
| SCHEMBL23455546 | 0.86 | ITGB1 (0.50) | ITGB1ITGA5ITGA4ITGB7ITGA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4072541-A1 | ALPHA-5 BETA-1 INHIBITORS | The Regents of the University of California (US) | 2022-10-19 | — | — | EP | disclosed |